Opening the black box of extracellular space
The central nervous system is made up of billions of cells. The cellular membranes create two broadly classified compartments, intracellular and extracellular space. Extracellular space occupies about a fifth of brain volume and it fills even the smallest gaps between cells. While the cells, their constituents, and even the movement of substances across the membranes have been widely studied, the complex 3D microenvironment surrounding the cells is still a largely uncharted frontier. NanoPSYCH is using new tools in nanotechnology and biotechnology to investigate the structure of the extracellular space and, in particular, how it affects the accumulation of autoantibodies. Autoimmunity has recently been linked to neuropsychiatric disorders and NanoPSYCH hopes to shed light on neurobiological mechanisms of such conditions.
Field of science
- /medical and health sciences/basic medicine/pathology
- /medical and health sciences/basic medicine/immunology
- /natural sciences/biological sciences/neurobiology
Call for proposal
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