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Neuropsychiatric disorders are a heterogeneous group of mental pathologies that demand prolonged and treatments that are frequently ineffective. Elucidating the cellular and molecular mechanisms under

Project description

Opening the black box of extracellular space

The central nervous system is made up of billions of cells. The cellular membranes create two broadly classified compartments, intracellular and extracellular space. Extracellular space occupies about a fifth of brain volume and it fills even the smallest gaps between cells. While the cells, their constituents, and even the movement of substances across the membranes have been widely studied, the complex 3D microenvironment surrounding the cells is still a largely uncharted frontier. NanoPSYCH is using new tools in nanotechnology and biotechnology to investigate the structure of the extracellular space and, in particular, how it affects the accumulation of autoantibodies. Autoimmunity has recently been linked to neuropsychiatric disorders and NanoPSYCH hopes to shed light on neurobiological mechanisms of such conditions.

Field of science

  • /medical and health sciences/basic medicine/pathology
  • /medical and health sciences/basic medicine/immunology
  • /natural sciences/biological sciences/neurobiology

Call for proposal

See other projects for this call

Funding Scheme

MSCA-IF-EF-ST - Standard EF
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Rue Michel Ange 3
75794 Paris
Activity type
Research Organisations
EU contribution
€ 196 707,84