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Predicting comorbid cardiovascular disease in individuals with mental disorder by decoding disease mechanisms

Deliverables

Quality Management Plan

Quality Management Plan

Innovation Management Plan

Innovation Management Plan

Protocols for distributed data analyses

Protocols for distributed data analyses in compliance with ethical, privacy, and GDPR regulations, with scalable technology.

Report on scientific outreach activities and public outreach activities - M12

Report on scientific outreach activities and public outreach activities. Including information on CoMorMent 6-monthly newsletters.

IP/Knowledge Management Plan

IP/Knowledge Management Plan

Dissemination, Exploitation and Communication Plan

Dissemination, Exploitation and Communication Plan and yearly updates. Including a description of CoMorMent website and Social Media channels operational.

Risk Management Plan

Risk Management Plan

CoMorMent Coordination team established

CoMorMent Coordination team established

Definition and harmonization of phenotypic and trajectories data from registries

Definition and harmonization of phenotypic and trajectories data from registries

Analytical tools for imputation and large-scale genotype-phenotype analysis

State-of-the-art analytical tools for imputation and large-scale genotype-phenotype analysis

Data platform for distributed data analysis

A secure data platform for distributed data analysis, including secure computing clusters for each country.

Annual Project Meeting - Y2

Meeting at DECODE Agenda+minutes

CoMorMent website and Social Media channels

The CoMorMent website is the key hub for providing detailed dissemination and communication material. The site will feature e.g. abstracts and lay summaries of scientific papers, newsletters, links to articles in popular science publications, and other material as outlined in Sections 2.2.1 and 2.2.5. CoMorMent will exploit social media for both dissemination and communication (Twitter, LinkedIn, Facebook, YouTube) purposes and to direct traffic to the project website. This task entails establishing the project website, Twitter, LinkedIn, Facebook accounts and a YouTube channel. All partners will provide material to be published. The partners will author a lay summary of the partner’s scientific articles for posting on the project website.

Searching for OpenAIRE data...

Publications

Disease trajectories and mortality among individuals diagnosed with depression: a community-based cohort study in UK Biobank

Author(s): Xin Han, Can Hou, Huazhen Yang, Wenwen Chen, Zhiye Ying, Yao Hu, Yajing Sun, Yuanyuan Qu, Lei Yang, Unnur A. Valdimarsdóttir, Wei Zhang, Haomin Yang, Fang Fang, Huan Song
Published in: Molecular Psychiatry, 2021, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-021-01170-6

Phenotypically independent profiles relevant to mental health are genetically correlated

Author(s): Daniel Roelfs, Dag Alnæs, Oleksandr Frei, Dennis van der Meer, Olav B. Smeland, Ole A. Andreassen, Lars T. Westlye, Tobias Kaufmann
Published in: Translational Psychiatry, 11/1, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-021-01313-x

Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms

Author(s): Linn Rødevand, Shahram Bahrami, Oleksandr Frei, Aihua Lin, Osman Gani, Alexey Shadrin, Olav B. Smeland, Kevin S. O’ Connell, Torbjørn Elvsåshagen, Adriano Winterton, Daniel S. Quintana, Guy F. L. Hindley, Maren C. F. Werner, Srdjan Djurovic, Anders M. Dale, Trine V. Lagerberg, Nils Eiel Steen, Ole A. Andreassen
Published in: Translational Psychiatry, 11/1, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-020-01142-4

Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes

Author(s): Linn Rødevand, Shahram Bahrami, Oleksandr Frei, Yunhan Chu, Alexey Shadrin, Kevin S. O’Connell, Olav B. Smeland, Torbjørn Elvsåshagen, Guy F. L. Hindley, Srdjan Djurovic, Anders M. Dale, Trine V. Lagerberg, Nils Eiel Steen, Ole A. Andreassen
Published in: Translational Psychiatry, 11/1, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-021-01527-z

Population-based body–brain mapping links brain morphology with anthropometrics and body composition

Author(s): Tiril P. Gurholt, Tobias Kaufmann, Oleksandr Frei, Dag Alnæs, Unn K. Haukvik, Dennis van der Meer, Torgeir Moberget, Kevin S. O’Connell, Olof D. Leinhard, Jennifer Linge, Rozalyn Simon, Olav B. Smeland, Ida E. Sønderby, Adriano Winterton, Nils Eiel Steen, Lars T. Westlye, Ole A. Andreassen
Published in: Translational Psychiatry, 11/1, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-021-01414-7

Using a knowledge exchange event to assess study participants’ attitudes to research in a rapidly evolving research context

Author(s): Iona Beange, Elizabeth J. Kirkham, Sue Fletcher-Watson, Matthew H. Iveson, Stephen M. Lawrie, G. David Batty, James P. Boardman, Ian J. Deary, Corri Black, David J. Porteous, Andrew M. McIntosh
Published in: Wellcome Open Research, 5, 2020, Page(s) 24, ISSN 2398-502X
Publisher: Welcome Open Research
DOI: 10.12688/wellcomeopenres.15651.2

Effects of copy number variations on brain structure and risk for psychiatric illness: Large‐scale studies from the ENIGMA working groups on CNVs

Author(s): Ida E. Sønderby, Christopher R. K. Ching, Sophia I. Thomopoulos, Dennis Meer, Daqiang Sun, Julio E. Villalon‐Reina, Ingrid Agartz, Katrin Amunts, Celso Arango, Nicola J. Armstrong, Rosa Ayesa‐Arriola, Geor Bakker, Anne S. Bassett, Dorret I. Boomsma, Robin Bülow, Nancy J. Butcher, Vince D. Calhoun, Svenja Caspers, Eva W. C. Chow, Sven Cichon, Simone Ciufolini, Michael C. Craig, Benedicto Cres
Published in: Human Brain Mapping, 2021, Page(s) online ahead of print, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25354

Co-development of a Best Practice Checklist for Mental Health Data Science: A Delphi Study

Author(s): Elizabeth J. Kirkham, Catherine J. Crompton, Matthew H. Iveson, Iona Beange, Andrew M. McIntosh, Sue Fletcher-Watson
Published in: Frontiers in Psychiatry, 12, 2021, ISSN 1664-0640
Publisher: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2021.643914

Genetic propensities for verbal and spatial ability have opposite effects on body mass index and risk of schizophrenia

Author(s): Gudrun A. Jonsdottir, Gudmundur Einarsson, Gudmar Thorleifsson, Sigurdur H. Magnusson, Arni F. Gunnarsson, Michael L. Frigge, Rosa S. Gisladottir, Unnur Unnsteinsdottir, Bjarni Gunnarsson, G. Bragi Walters, Valgerdur Steinthorsdottir, Anna Helgadottir, Ingileif Jonsdottir, Thorsteinn Gislason, Haraldur S. Thorsteinsson, Engilbert Sigurdsson, Magnus Haraldsson, Emil L. Sigurdsson, Ragnar Bjarnason,
Published in: Intelligence, 88, 2021, Page(s) 101565, ISSN 0160-2896
Publisher: Elsevier BV
DOI: 10.1016/j.intell.2021.101565

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

Author(s): Ida E. Sønderby, Dennis van der Meer, Clara Moreau, Tobias Kaufmann, G. Bragi Walters, Maria Ellegaard, Abdel Abdellaoui, David Ames, Katrin Amunts, Micael Andersson, Nicola J. Armstrong, Manon Bernard, Nicholas B. Blackburn, John Blangero, Dorret I. Boomsma, Henry Brodaty, Rachel M. Brouwer, Robin Bülow, Rune Bøen, Wiepke Cahn, Vince D. Calhoun, Svenja Caspers, Christopher R. K. Ching, Sven Ci
Published in: Translational Psychiatry, 11/1, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-021-01213-0