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A novel approach to non-invasive and personalized skin cancer diagnosis

Deliverables

Commercial launch

T4.2 and T4.4 will allow to accurately defining business and financial strategies of the company, as well as initiating discussions and collaborations with marketing partners and potential distributors, in order to maximize the commercial launch and market deployment of the OCTAV device.

CE mark

In T4.3, the most appropriate regulatory pathway will be explored to obtain the CE-mark in EU.

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Publications

Line-field confocal optical coherence tomography for three-dimensional skin imaging

Author(s): Jonas Ogien, Anthony Daures, Maxime Cazalas, Jean-Luc Perrot, Arnaud Dubois
Published in: Frontiers of Optoelectronics, 13/4, 2020, Page(s) 381-392, ISSN 2095-2759
Publisher: Springer Science + Business Media
DOI: 10.1007/s12200-020-1096-x

Konfokale Line-Field-OCT: die eierlegende Wollmilchsau?

Author(s): C. Ruini, E. Sattler
Published in: Aktuelle Dermatologie, 46/04, 2020, Page(s) 148-151, ISSN 0340-2541
Publisher: Georg Thieme Verlag
DOI: 10.1055/a-1072-7002

Line‐field confocal optical coherence tomography for non‐invasive diagnosis of lichenoid dermatoses of the childhood: A case series

Author(s): Linda Tognetti, Andrea. Carraro, Elisa Cinotti, Mariano Suppa, Veronique Marmol, Jean Luc Perrot, Pietro Rubegni
Published in: Skin Research and Technology, 2021, ISSN 0909-752X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/srt.13075

Caractérisation in vivo de la peau saine par tomographie confocale à cohérence optique en ligne (LC-OCT) : une nouvelle technique d’imagerie cutanée non-invasive en dermatologie

Author(s): J. Monnier, L. Tognetti, M. Miyamoto, M. Suppa, E. Cinotti, M. Fontaine, C. Orte Cano, J. Perez, O. Yelamos, V. Berot, P. Rubegni, S. Puig, V. Del Marmol, J. Malvehy, J.-L. Perrot
Published in: Annales de Dermatologie et de Vénéréologie, 147/12, 2020, Page(s) A207-A208, ISSN 0151-9638
Publisher: Elsevier Masson
DOI: 10.1016/j.annder.2020.09.257

La tomographie confocale à cohérence optique en ligne de la peau saine du visage : première étude descriptive

Author(s): J.-L. Perrot, M. Suppa, E. Cinotti, M. Fontaine, G. Dejonckheere, L. Tognetti, P. Rubegni, G. Diet, M. Miyamoto, C. Orte Cano, J. Monnier, V. Bérot, S. Puig, J. Perez Anker, J. Malvehy, V. Del Marmol, S. Forestier, G. Cazorla, J. Chauvel Picard
Published in: Annales de Dermatologie et de Vénéréologie, 147/12, 2020, Page(s) A208-A209, ISSN 0151-9638
Publisher: Elsevier Masson
DOI: 10.1016/j.annder.2020.09.259

Fulguration‐induced tattoo

Author(s): E. Cinotti, F. Bruzziches, C. Habougit, V. Berot, L. Tognetti, P. Rubegni, J. L. Perrot
Published in: Clinical and Experimental Dermatology, 45/7, 2020, Page(s) 911-912, ISSN 0307-6938
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ced.14288

Aspect en microscopie confocale par réflectance in vivo des kératoses actiniques

Author(s): J.L. Perrot, L. Tognetti, C. Habougit, A.C. Biron Schneider, C. Couzan, P. rubegni, e. Cinotti
Published in: Annales de Dermatologie et de Vénéréologie, 146, 2019, Page(s) IIS16-IIS21, ISSN 0151-9638
Publisher: Elsevier Masson
DOI: 10.1016/s0151-9638(19)30201-7

Line-field confocal optical coherence tomography (LC-OCT), une nouvelle technique d’imagerie cutanée non invasive pour le diagnostic du mélanome : une série de 27 lésions mélanocytaires

Author(s): J. Monnier, J. Perez, M. Suppa, E. Cinotti, L. Tognetti, V. Berot, P. Rubegni, V. Del Marmol, J.-L. Perrot, S. Puig, J. Malvehy
Published in: Annales de Dermatologie et de Vénéréologie, 147/12, 2020, Page(s) A80-A81, ISSN 0151-9638
Publisher: Elsevier Masson
DOI: 10.1016/j.annder.2020.09.020

The actinic dysplasia syndrome – diagnostic approaches defining a new concept in field carcinogenesis with multiple cSCC

Author(s): G. Dejonckheere, M. Suppa, V. Marmol, T. Meyer, E. Stockfleth
Published in: Journal of the European Academy of Dermatology and Venereology, 33/S8, 2019, Page(s) 16-20, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.15949

Line‐field confocal optical coherence tomography: a novel, non‐invasive imaging technique for a rapid, in‐vivo diagnosis of herpes infection of the skin

Author(s): F. Lacarrubba, A.E. Verzì, D.F. Puglisi, G. Micali
Published in: Journal of the European Academy of Dermatology and Venereology, 35/6, 2021, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.17182

Line‐field confocal optical coherence tomography of basal cell carcinoma: a descriptive study

Author(s): M. Suppa, M. Fontaine, G. Dejonckheere, E. Cinotti, O. Yélamos, G. Diet, L. Tognetti, M. Miyamoto, C. Orte Cano, J. Perez‐Anker, V. Panagiotou, A.L. Trepant, J. Monnier, V. Berot, S. Puig, P. Rubegni, J. Malvehy, J.L. Perrot, V. Marmol
Published in: Journal of the European Academy of Dermatology and Venereology, 35/5, 2021, Page(s) 1099-1110, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.17078

In vivo characterization of healthy human skin with a novel, non‐invasive imaging technique: line‐field confocal optical coherence tomography

Author(s): J. Monnier, L. Tognetti, M. Miyamoto, M. Suppa, E. Cinotti, M. Fontaine, J. Perez, C. Orte Cano, O. Yélamos, S. Puig, A. Dubois, P. Rubegni, V. Marmol, J. Malvehy, J.L. Perrot
Published in: Journal of the European Academy of Dermatology and Venereology, 2020, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.16857

Line‐field confocal optical coherence tomography for actinic keratosis and squamous cell carcinoma: a descriptive study

Author(s): E. Cinotti, L. Tognetti, A. Cartocci, A. Lamberti, S. Gherbassi, C. Orte Cano, C. Lenoir, G. Dejonckheere, G. Diet, M. Fontaine, M. Miyamoto, J. Perez‐Anker, V. Solmi, J. Malvehy, V. Marmol, J. L. Perrot, P. Rubegni, M. Suppa
Published in: Clinical and Experimental Dermatology, 2021, ISSN 0307-6938
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ced.14801

Examination of circumscribed palmar hypokeratosis with line-field confocal optical coherence tomography: Dermoscopic, ultrasonographic and histopathologic correlates

Author(s): Linda Tognetti, Diletta Fiorani, Mariano Suppa, Elisa Cinotti, Margot Fontaine, VeroniqueDel Marmol, Pietro Rubegni, JeanLuc Perrot
Published in: Indian Journal of Dermatology, Venereology and Leprology, 86/2, 2020, Page(s) 206, ISSN 0378-6323
Publisher: Medknow Publications
DOI: 10.4103/ijdvl.ijdvl_546_19

Line‐field confocal optical coherence tomography of benign dermal melanocytic proliferations: a case series

Author(s): C. Lenoir, J. Perez‐Anker, G. Diet, L. Tognetti, E. Cinotti, A.L. Trépant, P. Rubegni, S. Puig, J.L. Perrot, J. Malvehy, V. Marmol, M. Suppa
Published in: Journal of the European Academy of Dermatology and Venereology, 35/6, 2021, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.17180

Delayed Tattoo Reaction From Red Dye With Overlapping Clinicopathological Features: Examination With High-Frequency Ultrasound and Line-Field Optical Coherence Tomography

Author(s): Linda Tognetti, Sean Ekinde, Cyril Habougit, Elisa Cinotti, Pietro Rubegni, Jean Luc Perrot
Published in: Dermatology Practical & Conceptual, 2020, Page(s) e2020053, ISSN 2160-9381
Publisher: Dermatololgy Practical & Conceptual
DOI: 10.5826/dpc.1003a53

Line field confocal optical coherence tomography: An adjunctive tool in the diagnosis of autoimmune bullous diseases

Author(s): Linda Tognetti, Elisa Cinotti, Mariano Suppa, Raffaella Guazzo, Cyril Habougit, Francesco Santi, Gwendoline Diet, Margot Fontaine, Vincent Berot, Jilliana Monnier, Elisa Pianigiani, Véronique Marmol, Joseph Malvehy, Jean‐Luc Perrot, Pietro Rubegni
Published in: Journal of Biophotonics, 2021, ISSN 1864-063X
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.202000449

Comparison of line‐field confocal optical coherence tomography images with histological sections: Validation of a new method for in vivo and non‐invasive quantification of superficial dermis thickness

Author(s): Mélanie Pedrazzani, Josselin Breugnot, Pauline Rouaud‐Tinguely, Maxime Cazalas, Arthur Davis, Sylvie Bordes, Arnaud Dubois, Brigitte Closs
Published in: Skin Research and Technology, 26/3, 2020, Page(s) 398-404, ISSN 0909-752X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/srt.12815

New findings in non‐invasive imaging of aquagenic keratoderma: Line‐field optical coherence tomography, dermoscopy and reflectance confocal microscopy

Author(s): Linda Tognetti, Arianna Rizzo, Diletta Fiorani, Elisa Cinotti, Jean Luc Perrot, Pietro Rubegni
Published in: Skin Research and Technology, 2020, ISSN 0909-752X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/srt.12882

Dual-mode line-field confocal optical coherence tomography for ultrahigh-resolution vertical and horizontal section imaging of human skin in vivo

Author(s): Jonas Ogien, Olivier Levecq, Hicham Azimani, Arnaud Dubois
Published in: Biomedical Optics Express, 11/3, 2020, Page(s) 1327, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.385303

In vivo imaging of Sarcoptes scabiei infestation using line‐field confocal optical coherence tomography

Author(s): C. Ruini, S. Schuh, G. Pellacani, L. French, J. Welzel, E. Sattler
Published in: Journal of the European Academy of Dermatology and Venereology, 2020, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.16671

Line‐field confocal optical coherence tomography—Practical applications in dermatology and comparison with established imaging methods

Author(s): Cristel Ruini, Sandra Schuh, Elke Sattler, Julia Welzel
Published in: Skin Research and Technology, 27/3, 2021, Page(s) 340-352, ISSN 0909-752X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/srt.12949

Mirau-based line-field confocal optical coherence tomography

Author(s): Arnaud Dubois, Weikai Xue, O. Levecq, P. Bulkin, Anne-Lise Coutrot, Jonas Ogien
Published in: Optics Express, 28/6, 2020, Page(s) 7918, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.389637

Line‐field confocal optical coherence tomography of sebaceous hyperplasia: a case series

Author(s): C. Lenoir, G. Diet, E. Cinotti, L. Tognetti, C. Orte Cano, L. Rocq, A.‐L. Trépant, J. Monnier, J. Perez‐Anker, P. Rubegni, S. Puig, J. Malvehy, J.‐L. Perrot, V. Marmol, M. Suppa
Published in: Journal of the European Academy of Dermatology and Venereology, 35/8, 2021, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.17251

Noninvasive real‐time imaging of mite skin infestations with line‐field confocal optical coherence tomography

Author(s): C. Ruini, S. Schuh, D. Hartmann, L. French, J. Welzel, E. Sattler
Published in: British Journal of Dermatology, 184/1, 2021, ISSN 0007-0963
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjd.19318

Tridimensional skin imaging in aquagenic keratoderma: virtual histology by line‐field confocal optical coherence tomography

Author(s): Linda Tognetti, Diletta Fiorani, Elisa Cinotti, Pietro Rubegni
Published in: International Journal of Dermatology, 2020, ISSN 0011-9059
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ijd.15169

Line‐field confocal optical coherence tomography in molluscum contagiosum: a case series

Author(s): A.E. Verzì, G. Micali, F. Lacarrubba
Published in: Journal of the European Academy of Dermatology and Venereology, 2021, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.17594

Line‐field optical coherence tomography: in vivo diagnosis of basal cell carcinoma subtypes compared with histopathology

Author(s): C. Ruini, S. Schuh, C. Gust, B. Kendziora, L. Frommherz, L. E. French, D. Hartmann, J. Welzel, E. Sattler
Published in: Clinical and Experimental Dermatology, 2021, ISSN 0307-6938
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ced.14762

Line‐field confocal optical coherence tomography of xanthogranuloma: Correlation with vertical and horizontal histopathology

Author(s): Francesco Lacarrubba, Anna Elisa Verzì, Davide Francesco Puglisi, Giuseppe Broggi, Rosario Caltabiano, Giuseppe Micali
Published in: Journal of Cutaneous Pathology, 48/9, 2021, Page(s) 1208-1211, ISSN 0303-6987
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cup.14067

In-Vivo LC-OCT Evaluation of the Downward Proliferation Pattern of Keratinocytes in Actinic Keratosis in Comparison with Histology: First Impressions from a Pilot Study

Author(s): Cristel Ruini, Sandra Schuh, Charlotte Gust, Daniela Hartmann, Lars Einar French, Elke Christina Sattler, Julia Welzel
Published in: Cancers, 13/12, 2021, Page(s) 2856, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13122856