Dissecting the chromatin response to DNA damage in silenced heterochromatin regions

Project Information

CHROMREP

Grant agreement ID: 850405

DOI

10.3030/850405

Project closed

EC signature date 14 November 2019

Start date 1 December 2019

End date 31 May 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 404,00

EU contribution

€ 1 499 404,00

Coordinated by

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

The Sound of Silence: How Silenced Chromatin Orchestrates the Repair of Double-Strand Breaks.

Author(s): Apfrida Kendek; Marieke R Wensveen; Aniek Janssen
Published in: Genes, Issue 1, 2021, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes12091415

The impact of chromatin on double-strand break repair: Imaging tools and discoveries

Author(s): Marit van Bueren, Aniek Janssen
Published in: DNA repair, 2023, ISSN 1568-7864
Publisher: Elsevier BV
DOI: 10.1016/j.dnarep.2023.103592

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Author(s): Marieke R. Wensveen, Aditya A. Dixit, Robin van Schendel, Apfrida Kendek, Jan-Paul Lambooij, Marcel Tijsterman, Serafin U. Colmenares, Aniek Janssen
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-53313-2

Polymorphic transposable elements contribute to variation in recombination landscapes

Author(s): Yuheng Huang, Zita Y. Gao, Kayla Ly, Leila Lin, Jan-Paul Lambooij, Elizabeth G. King, Aniek Janssen, Kevin H.-C. Wei, Yuh Chwen G. Lee
Published in: Proceedings of the National Academy of Sciences, Issue 122, 2025, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2427312122

DNA double-strand break movement in heterochromatin depends on the histone acetyltransferase dGcn5

Author(s): Apfrida Kendek, Arianna Sandron, Jan-Paul Lambooij, Serafin U Colmenares, Severina M Pociunaite, Iris Gooijers, Lars de Groot, Gary H Karpen, Aniek Janssen
Published in: Nucleic Acids Research, Issue 52, 2024, Page(s) 11753-11767, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkae775

Other (3)

DNA Double-Strand Break Movement in Heterochromatin Depends on the Drosophila Histone Acetyltransferase Gcn5

Author(s): Apfrida Kendek, Arianna Sandron, Jan-Paul Lambooij, Serafin U. Colmenares, Paula Sobrevals Alcaraz, Robert van Es, Severina M. Pociunaite, Iris Gooijers, Lars de Groot, Gary H. Karpen, Aniek Janssen
Published in: 2023
Publisher: BioRxiv
DOI: 10.1101/2023.11.30.569406

Varying recombination landscapes between individuals are driven by polymorphic transposable elements

Author(s): Yuheng Huang, Yi Gao, Kayla Ly, Leila Lin, Jan Paul Lambooij, Elizabeth G. King, Aniek Janssen, Kevin H.-C. Wei, Yuh Chwen G. Lee
Published in: 2024
Publisher: BioRxiv
DOI: 10.1101/2024.09.17.613564

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Author(s): Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, View ORCID ProfileAniek Janssen
Published in: 2023
Publisher: BioRxiv
DOI: 10.1101/2023.12.01.569547