Gut-Brain Communication in Metabolic Control

Project description

Gut-brain communication and obesity

Neural gut-brain communication helps to monitor gastrointestinal organs and contributes to energy and glucose homeostasis regulation. Its disruption develops in obesity and correlates with overeating and insulin resistance. This EU-funded project will employ a combination of modern molecular neuroscience tools and mouse genetic approaches to determine the identity of gut-innervating neurons, define their role in feeding behaviour and glucose metabolism, and map the neurocircuitry to downstream brain sites. Successful outcome of the project will help to overcome challenges associated with targeting distinct neurons in a cell-type and organ-specific manner, an important first step to developing new therapies to treat obesity.

Fields of science

• medical and health sciences › health sciences › nutrition › obesity

Programme(s)

• H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme

Topic(s)

• ERC-2019-STG - ERC Starting Grant

Call for proposal

ERC-2019-STG

See other projects for this call

Funding Scheme

ERC-STG - Starting Grant

Host institution

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

Net EU contribution

€ 1 500 000,00

Address

Hofgartenstrasse 8
80539 Munchen
Germany

Activity type

Research Organisations

Non-EU contribution

€ 0,00

Region

Bayern › Oberbayern › München, Kreisfreie Stadt

Beneficiaries (1)

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

Germany

Net EU contribution

€ 1 500 000,00

Address

Hofgartenstrasse 8
80539 Munchen

Activity type

Research Organisations

Non-EU contribution

€ 0,00

Region

Bayern › Oberbayern › München, Kreisfreie Stadt