Dynamic Growth and Replication in Coacervate Protocells

Project Information

DynaGrow

Grant agreement ID: 851963

DOI 10.3030/851963

EC signature date 8 October 2019

Start date 1 March 2020

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

STICHTING RADBOUD UNIVERSITEIT
Netherlands

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Participation in the Open Research Data Pilot

Publications

Peer reviewed articles (8)

A short peptide synthon for liquid-liquid phase separation

Author(s): Manzar Abbas, Wojciech P. Lipiński, Karina K. Nakashima, Wilhelm T. S. Huck and Evan Spruijt
Published in: Nature Chemistry, Issue 17554330, 2021, Page(s) 1046-1054, ISSN 1755-4330
Publisher: Nature Publishing Group
DOI: 10.1038/s41557-021-00788-x

Fibrils Emerging from Droplets: Molecular Guiding Principles behind Phase Transitions of a Short Peptide-Based Condensate Studied by Solid-State NMR

Author(s): Wojciech P. Lipiński, Johannes Zehnder, Manzar Abbas, Peter Güntert, Evan Spruijt, Thomas Wiegand
Published in: Chemistry A European Journal, Issue 29, 2023, Page(s) e202301159, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202301159

Peptide‐Based Coacervate‐Core Vesicles with Semipermeable Membranes

Author(s): Manzar Abbas; Jack O. Law; Sushma N. Grellscheid; Wilhelm T. S. Huck; Evan Spruijt
Published in: Advanced Materials, Issue 15214095, 2022, Page(s) 2202913, ISSN 1521-4095
Publisher: Wiley Inc
DOI: 10.1002/adma.202202913

Complex coacervation and compartmentalized conversion of prebiotically relevant metabolites

Author(s): Iris B. A. Smokers, Merlijn H. I. van Haren, Tiemei Lu and Evan Spruijt
Published in: ChemSystemsChem, Issue 25704206, 2022, Page(s) e202200004, ISSN 2570-4206
Publisher: Wiley-VCH
DOI: 10.1002/syst.202200004

Growth, replication and division enable evolution of coacervate protocells

Author(s): Annemiek D. Slootbeek, Merlijn H. I. van Haren, Iris B. A. Smokers and Evan Spruijt
Published in: Chemical Communications, Issue 1364548X, 2022, Page(s) 11183-11200, ISSN 1364-548X
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2cc03541c

Open questions on liquid–liquid phase separation

Author(s): Evan Spruijt
Published in: Communcations Chemistry, Issue 1, 2023, Page(s) 23, ISSN 2399-3669
Publisher: Springer Nature
DOI: 10.1038/s42004-023-00823-7

Aqueous coordination polymer complexes: From colloidal assemblies to bulk materials

Author(s): Jiahua Wang, Tiemei Lu,Yuehua Li, Junyou Wang, Evan Spruijt
Published in: Advances in Colloid and Interface Science, Issue 318, 2023, Page(s) 102964, ISSN 0001-8686
Publisher: Elsevier BV
DOI: 10.1016/j.cis.2023.102964

Peptide-based coacervates as biomimetic protocells

Author(s): Manzar Abbas; Wojciech P. Lipiński; Jiahua Wang; Evan Spruijt
Published in: Chemical Society Reviews, Issue 1, 2021, ISSN 0306-0012
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0cs00307g

Non-peer reviewed articles (1)

Peptide-based liquid droplets as emerging delivery vehicles

Author(s): Jianhui Liu, Evan Spruijt, Ali Miserez, Robert Langer
Published in: Nature Reviews Materials, Issue 8, 2023, Page(s) 139-141, ISSN 2058-8437
Publisher: Nature Publishing Group
DOI: 10.1038/s41578-022-00528-8