The Function of Hippocampal and Cortical Memory Replay in Humans

Project Information

REPLAY

Grant agreement ID: 852669

DOI

10.3030/852669

EC signature date 26 February 2020

Start date 1 April 2020

End date 30 September 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 416 506,00

EU contribution

€ 1 416 506,00

Coordinated by

UNIVERSITY OF HAMBURG
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (26)

Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence

Author(s): Nir Moneta, Mona M. Garvert, Hauke R. Heekeren, Nicolas W. Schuck
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-38709-w

Control over patch encounters changes foraging behavior

Author(s): Sam Hall-McMaster; Peter Dayan; Nicolas W. Schuck
Published in: iScience, Issue Volume 24, Issue 9, 24 September 2021, 2021, Page(s) 103005, ISSN 2589-0042
Publisher: Cell Press Elsevier Inc.
DOI: 10.1016/j.isci.2021.103005

Dopamine differentially modulates medial temporal lobe activity and behavior during spatial navigation in young and older adults

Author(s): Christian Baeuchl, Franka Glöckner, Christoph Koch, Johannes Petzold, Nicolas W. Schuck, Michael N. Smolka, Shu-Chen Li
Published in: NeuroImage, Issue 273, 2024, Page(s) 120099, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2023.120099

BrainIAK: The Brain Imaging Analysis Kit

Author(s): Manoj Kumar, Michael J Anderson, James W Antony, Christopher Baldassano, Paula P Brooks, Ming Bo Cai, Po-Hsuan Cameron Chen, Cameron T Ellis, Gregory Henselman-Petrusek, David Huberdeau, J Benjamin Hutchinson, Peeta Y Li, Qihong Lu, Jeremy R Manning, Anne C Mennen, Samuel A Nastase, Hugo Richard, Anna C Schapiro, Nicolas W Schuck, Michael Shvartsman, Narayanan Sundaram, Daniel Suo, Javier S Turek,
Published in: Aperture Neuro, 2021, ISSN 2373-2822
Publisher: OHBM
DOI: 10.31219/osf.io/db2ev

An inductive bias for slowly changing features in human reinforcement learning

Author(s): Noa L. Hedrich, Eric Schulz, Sam Hall-McMaster, Nicolas W. Schuck
Published in: PLOS Computational Biology, Issue 20, 2024, Page(s) e1012568, ISSN 1553-7358
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/journal.pcbi.1012568

Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization

Author(s): Mona M. Garvert, Tankred Saanum, Eric Schulz, Nicolas W. Schuck, Christian F. Doeller
Published in: Nature Neuroscience, Issue 26, 2023, Page(s) 615-626, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-023-01283-x

Decoding cognition from spontaneous neural activity

Author(s): Yunzhe Liu Matthew M Nour Nicolas W Schuck Timothy E Behrens Ray J Dolan
Published in: Nature Reviews Neuroscience, Issue 23(4), 2022, Page(s) 204-214, ISSN 1471-003X
Publisher: Nature Publishing Group
DOI: 10.1038/s41583-022-00570-z

Orbitofrontal cortex and learning predictions of state transitions

Author(s): Stephanie C. Y. Chan; Nicolas W. Schuck; Nina Lopatina; Geoffrey Schoenbaum; Yael Niv
Published in: Behavioral Neuroscience, Issue 135, 2021, Page(s) 487–497, ISSN 0735-7044
Publisher: American Psychological Association
DOI: 10.1101/2020.09.17.302521

The dorsomedial prefrontal cortex represents subjective value across effort-based and risky decision-making

Author(s): Yuan-Wei Yao, Kun-Ru Song, Nicolas W. Schuck, Xin Li, Xiao-Yi Fang, Jin-Tao Zhang, Hauke R. Heekeren, Rasmus Bruckner
Published in: NeuroImage, Issue 279, 2024, Page(s) 120326, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2023.120326

Trait anxiety is associated with hidden state inference during aversive reversal learning

Author(s): Ondrej Zika, Katja Wiech, Andrea Reinecke, Michael Browning, Nicolas W. Schuck
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-39825-3

N2 sleep promotes the occurrence of ‘aha’ moments in a perceptual insight task

Author(s): Anika T. Löwe, Marit Petzka, Maria M. Tzegka, Nicolas W. Schuck
Published in: PLOS Biology, Issue 23, 2025, Page(s) e3003185, ISSN 1545-7885
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/journal.pbio.3003185

Entorhinal cortex signals dimensions of past experience that can be generalised in a novel environment

Author(s): Sam Hall-McMaster, Lennart Wittkuhn, Luianta Verra, Noa L. Hedrich, Kazuki Irie, Peter Dayan, Samuel J. Gershman, Nicolas W. Schuck
Published in: Journal of Neuroscience, 2026, ISSN 1529-2401
Publisher: Society for Neuroscience
DOI: 10.1101/2025.08.01.668096

Goal-seeking compresses neural codes for space in the human hippocampus and orbitofrontal cortex

Author(s): PS Muhle-Karbe, H Sheahan, G Pezzulo, H Spiers, S Chien, NW Schuck, C Summerfield
Published in: Neuron, 2024, ISSN 1097-4199
Publisher: Cell Press
DOI: 10.1101/2023.01.12.523762

Replay in the human visual cortex during brief task pauses is linked to implicit learning of successor representations

Author(s): Lennart Wittkuhn, Lena M. Krippner, Christoph Koch, Nicolas W. Schuck
Published in: Proceedings of the National Academy of Sciences, Issue 122, 2025, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2507516122

L-DOPA enhances neural direction signals in younger and older adults

Author(s): Christoph Koch; Christian Baeuchl; Franka Glöckner; Philipp Riedel; Johannes Petzold; Michael N Smolka; Shu-Chen Li; Nicolas W Schuck
Published in: NeuroImage, Issue 264, 2022, Page(s) 119670, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2022.119670

Neural evidence that humans reuse strategies to solve new tasks

Author(s): Sam Hall-McMaster, Momchil S. Tomov, Samuel J. Gershman, Nicolas W. Schuck
Published in: PLOS Biology, Issue 23, 2025, Page(s) e3003174, ISSN 1545-7885
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/journal.pbio.3003174

Differential prioritization of intramaze cue and boundary information during spatial navigation across the human lifespan

Author(s): Glöckner, Franka; Schuck, Nicolas W.; Li, Shu-Chen
Published in: Scientific Reports, Issue Vol 11, Issue 1, 2021, Page(s) 1-16, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-94530-9

Grid-like entorhinal representation of an abstract value space during prospective decision making

Author(s): Alexander Nitsch, Mona M. Garvert, Jacob L. S. Bellmund, Nicolas W. Schuck, Christian F. Doeller
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-45127-z

Replay in minds and machines

Author(s): Lennart Wittkuhn, Samson Chien, Sam Hall-McMaster, Nicolas W. Schuck
Published in: Neuroscience & Biobehavioral Reviews, Issue 129, 2021, Page(s) 367-388, ISSN 0149-7634
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2021.08.002

Interfacing with the Brain: How Nanotechnology Can Contribute

Author(s): Abdullah A. A. Ahmed, Nuria Alegret, Bethany Almeida, Ramón Alvarez-Puebla, Anne M. Andrews, Laura Ballerini, Juan J. Barrios-Capuchino, Charline Becker, Robert H. Blick, Shahin Bonakdar, Indranath Chakraborty, Xiaodong Chen, Jinwoo Cheon, Gerwin Chilla, Andre Luiz Coelho Conceicao, James Delehanty, Martin Dulle, Alexander L. Efros, Matthias Epple, Mark Fedyk, Neus Feliu, Miao Feng, Rafael Ferná
Published in: ACS Nano, Issue 19, 2025, Page(s) 10630-10717, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.4c10525

Spontaneous discovery of novel task solutions in children

Author(s): Nicolas W. Schuck; Amy X. Li; Dorit Wenke; Destina S. Ay-Bryson; Anika T. Loewe; Robert Gaschler; Yee Lee Shing
Published in: PLoS ONE, Issue 1, 2022, Page(s) e0266253, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0266253

Abrupt and spontaneous strategy switches emerge in simple regularised neural networks

Author(s): Anika T. Löwe, Léo Touzo, Paul S. Muhle-Karbe, Andrew M. Saxe, Christopher Summerfield, Nicolas W. Schuck
Published in: PLoS Computational Biology, 2024, ISSN 1553-7358
Publisher: Public Library of Science
DOI: 10.48550/arxiv.2302.11351

Dynamics of fMRI patterns reflect sub-second activation sequences and reveal replay in human visual cortex

Author(s): Lennart Wittkuhn, Nicolas W. Schuck
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-21970-2

Similarities and differences in spatial and non-spatial cognitive maps

Author(s): Charley M. Wu, Eric Schulz, Mona M. Garvert, Björn Meder, Nicolas W. Schuck
Published in: PLOS Computational Biology, Issue 16/9, 2020, Page(s) e1008149, ISSN 1553-7358
Publisher: PLOS
DOI: 10.1371/journal.pcbi.1008149

Representational spaces in orbitofrontal and ventromedial prefrontal cortex: task states, values, and beyond

Author(s): Nir Moneta, Shany Grossman, Nicolas W. Schuck
Published in: Trends in Neurosciences, Issue 47, 2024, Page(s) 1055-1069, ISSN 0166-2236
Publisher: Elsevier BV
DOI: 10.1016/j.tins.2024.10.005

Influence of surprise on reinforcement learning in younger and older adults

Author(s): Christoph Koch, Ondrej Zika, Rasmus Bruckner, Nicolas W. Schuck
Published in: PLOS Computational Biology, Issue 20, 2024, Page(s) e1012331, ISSN 1553-7358
Publisher: Public Library of Science
DOI: 10.1371/journal.pcbi.1012331

Book chapters (1)

Neuroscience Methods for Investigating Brain Plasticity (Chapter to appear in The Oxford Handbook of Cognitive Enhancement and Brain Plasticity)

Author(s): Luianta Verra, Fabian Renz, Nicolas W Schuck
Published in: The Oxford Handbook of Cognitive Enhancement and Brain Plasticity, 2025
Publisher: Oxford University Press
DOI: 10.31234/osf.io/9unem

Conference proceedings (1)

A blocked learning curriculum reduces age-related deficits in memory

Author(s): Xiangjuan Ren, Marit Petzka; Nicolas Schuck
Published in: Proceedings of the Annual Meeting of the Cognitive Science Society, Issue 46, 2024
Publisher: eScholarship

Other (4)

An inductive bias for slowly changing features in human reinforcement learning

Author(s): Noa L. Hedrich, Eric Schulz, Sam Hall-McMaster, Nicolas W. Schuck
Published in: bioRxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.01.24.576910

N2 Sleep Inspires Insight

Author(s): Anika T. Löwe, Marit Petzka, Maria Tzegka, Nicolas W. Schuck
Published in: bioRxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.06.24.600359

Neural Prioritisation of Past Solutions Supports Generalisation

Author(s): Sam Hall-McMaster, Momchil S. Tomov, Samuel J. Gershman, Nicolas W. Schuck
Published in: bioRxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.06.10.598294

Replay in human visual cortex is linked to the formation of successor representations and independent of consciousness

Author(s): Lennart Wittkuhn, Lena M. Krippner, Christoph Koch, Nicolas W. Schuck
Published in: bioRxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.02.02.478787