Coat assembly and membrane remodelling: understanding regulation of protein secretion

Project Information

CRYTOCOP

Grant agreement ID: 852915

DOI

10.3030/852915

Project closed

EC signature date 2 October 2019

Start date 1 November 2019

End date 30 April 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 175,00

EU contribution

€ 1 499 175,00

Coordinated by

BIRKBECK COLLEGE - UNIVERSITY OF LONDON
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan (DMP)

Data Management Plan DMP

Publications

Peer reviewed articles (8)

The small <scp>GTPase</scp> Sar1, control centre of <scp>COPII</scp> trafficking

Author(s): Sander E. Van der Verren, Giulia Zanetti
Published in: FEBS Letters, Issue 597, 2023, Page(s) 865-882, ISSN 0014-5793
Publisher: Elsevier BV
DOI: 10.1002/1873-3468.14595

Cryo-electron tomography reveals how COPII assembles on cargo-containing membranes

Author(s): Euan Pyle, Elizabeth A. Miller, Giulia Zanetti
Published in: Nature Structural and Molecular Biology, 2026, ISSN 1545-9985
Publisher: Springer Nature
DOI: 10.1101/2024.01.17.576008

A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0

Author(s): Jasenko Zivanov, Joaquín Otón, Zunlong Ke, Andriko von Kügelgen, Euan Pyle, Kun Qu, Dustin Morado, Daniel Castaño-Díez, Giulia Zanetti, Tanmay AM Bharat, John AG Briggs, Sjors HW Scheres
Published in: eLife, Issue 11, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.83724

Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network

Author(s): Joshua Hutchings, Viktoriya G. Stancheva, Nick R. Brown, Alan C. M. Cheung, Elizabeth A. Miller, Giulia Zanetti
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22110-6

Strategies for Picking Membrane-Associated Particles within Subtomogram Averaging Workflows

Author(s): Euan Pyle, Giulia Zanetti
Published in: Faraday Discussions, 2022, ISSN 1359-6640
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2fd00022a

Mechanisms of COPII coat assembly and cargo recognition in the secretory pathway

Author(s): Katie W. Downes, Giulia Zanetti
Published in: Nature Reviews Molecular Cell Biology, Issue 26, 2025, Page(s) 910-925, ISSN 1471-0072
Publisher: Nature Publishing Group
DOI: 10.1038/s41580-025-00839-y

Combinatorial multivalent interactions drive cooperative assembly of the COPII coat.

Author(s): Viktoriya G. Stancheva; Xiao-Han Li; Joshua Hutchings; Natalia Gomez-Navarro; Balaji Santhanam; M. Madan Babu; Giulia Zanetti; Elizabeth A. Miller
Published in: The Journal of Cell Biology, Issue 1, 2020, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.202007135

Current data processing strategies for cryo-electron tomography and subtomogram averaging

Author(s): Euan Pyle, Giulia Zanetti
Published in: Biochemical Journal, Issue 478, 2021, Page(s) 1827-1845, ISSN 0264-6021
Publisher: Portland Press, Ltd.
DOI: 10.1042/bcj20200715

Other (1)

Multi-scale Molecular Imaging of Human Cells reveals COPI and COPII Vesicles at ER Exit Sites

Author(s): Katie Downes, Julia Flood, Andrea Nans, Sander Van der Verren, Anjon Audhya, Giulia Zanetti
Published in: 2026
Publisher: openRxiv
DOI: 10.1101/2025.07.29.667472