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A High-throughput, Functional Imaging Platform to Accelerate Drug Discovery

Project description

Novel platform at the service of drug discovery for brain disease

Most techniques for functional imaging either interfere with cellular viability and physiology or provide poor resolution. To address these limitations, scientists of the EU-funded Ima-Go project have investigated the commercial feasibility of a 96-well platform that is label-free, non-invasive and can be used with live human cells for high-quality readouts. The platform uses electrodes to track neuronal activity, offering a novel solution for pharmaceutical companies interested in drug development for brain diseases. The Ima-Go project will further scale this technology to a high-throughput platform required in the drug discovery pipeline and introduce novel biological assays that cannot be performed by current competing technologies.

Objective

The aim of this SME Instruments Phase 1 proposal is to perform a feasibility study for the commercialization of Ima-Go, a novel 96-well functional imaging platform for preclinical drug discovery for substances targeting brain diseases.
In contrast to state-of-the-art technologies for functional imaging, which either interfere with cellular viability and physiology or provide only a poor spatiotemporal resolution, Ima-Go is label-free, non-invasive and provides readouts of highest quality and resolution. The Ima-Go platform will introduce to the market new biological assays for human cell lines, which cannot be performed by current competing technologies.

MaxWell Biosystems AG developed the most advanced functional imaging platform for tracking neuronal activity used in basic neuroscience research. With Ima-Go, MaxWell Biosystem will scale this technology to a throughput required in drug discovery applications. MaxWell Biosystems AG aims to become a world-wide technology leader in the field of advanced functional imaging platforms and modern data analysis solutions, meeting the needs of pharmaceutical companies and contract research organizations to accelerate drug development.

Fields of science (EuroSciVoc)

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SME-1 - SME instrument phase 1

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-EIC-SMEInst-2018-2020

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Coordinator

MAXWELL BIOSYSTEMS AG
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 50 000,00
Address
ALBISRIEDERSTRASSE 253
8047 Zurich
Switzerland

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 71 429,00
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