Objective
We propose a theoretical study of dynamical aspects of molecular cell biology using techniques available from statistical physics, nonlinear dynamics and numerical simulation. As a complementary focus, we suggest independent studies on the dynamical critic al phenomena of stochastic systems.
The objective is to develop appropriate theoretical techniques using standard models in a statistical physics framework, eg. dynamically growing interfaces, granular systems, etc. and then to utilise these well tested techniques on the target biological systems. Our major motivation is to study the dynamical properties of cytoskeletons, the filamentous protein network found in the cytoplasm of eukaryotic cells.
The focus problems will be the dynamics of cilia and flagella , the hair like cellular appendages driven by molecular motors and the dynamics of cytoskeletal fibres during the non-equilibrium polymerisation of protofilaments and mitotic cell division. The flagellar dynamics has two-fold significance, that concerning the reproductive process through the fertilisation of an ovum by a sperm and the other concerning the hearing mechanism.
Both processes are powered by molecular motors and are generally believed to be self-organising in nature. Utilising these fundamental symmetry principles and standard techniques from statistical and nonlinear physics, our goal is to develop a generalised theory which is able to reproduce the detailed dynamics by taking into account all relevant deterministic and stochastic contributions concerning flagellar motion.
A closely related interest will be a study of the lung ventilation technique, a medical method to measure the lung volume of patients suffering from lung diseases. All theoretical predictions will frequently be cross-checked against experimental results available from leading laboratories.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences theoretical physics particle physics
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences cell biology
- natural sciences chemical sciences polymer sciences
- natural sciences physical sciences classical mechanics statistical mechanics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-7
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
IIF - Marie Curie actions-Incoming International Fellowships
Coordinator
PADOVA
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.