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Ionic Neuromodulation For Epilepsy Treatment

Project description

Revolutionary approach to treat drug-resistant epilepsy

Around 30 % of patients with epilepsy have a drug-resistant form of the disease. In this condition, even two anti-epileptic drugs are unable to achieve freedom from seizure when prescribed as mono-therapies or in combination. Currently, there is no approach that has produced meaningful improvement in such patients. This EU-funded consortium is developing a totally new approach to manipulate neuronal cell excitability – applying neuronal firing by direct ionic actuation at the microscopic scale and monitoring cell responses by nanoscale transistors. This multidisciplinary consortium aims to establish proof-of-principle for breakthrough neuromodulation technology by enabling future brain implants for epilepsy treatment through in vitro testing of special polymers and ultra-sensitive ion sensor arrays.

Field of science

  • /natural sciences/chemical sciences/electrochemistry
  • /natural sciences/chemical sciences/inorganic chemistry/inorganic compounds
  • /medical and health sciences/basic medicine/neurology/epilepsy
  • /natural sciences/chemical sciences/polymer science
  • /engineering and technology/nanotechnology
  • /natural sciences/biological sciences/biophysics
  • /engineering and technology/nanotechnology/nanoelectronics
  • /medical and health sciences/medical biotechnology/medical bioproducts/implants
  • /natural sciences/biological sciences/neurobiology
  • /natural sciences/biological sciences/neurobiology/neuroscience

Call for proposal

H2020-FETOPEN-2018-2019-2020-01
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE
Address
Via Bonomea 265
34136 Trieste
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 847 812,50

Participants (5)

UNIVERSITE DE GENEVE
Switzerland
EU contribution
€ 498 290
Address
Rue Du General Dufour 24
1211 Geneve
Activity type
Higher or Secondary Education Establishments
IBM RESEARCH GMBH
Switzerland
EU contribution
€ 800 562,50
Address
Saeumerstrasse 4
8803 Rueschlikon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE UNIVERSITY OF SHEFFIELD
United Kingdom
EU contribution
€ 569 238,75
Address
Firth Court Western Bank
S10 2TN Sheffield
Activity type
Higher or Secondary Education Establishments
CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LA NANOELETTRONICA
Italy
EU contribution
€ 430 000
Address
Via Toffano 2
40125 Bologna
Activity type
Research Organisations
MULTI CHANNEL SYSTEMS MCS GMBH
Germany
EU contribution
€ 223 855
Address
Aspenhaustrasse 21
72770 Reutlingen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)