CORDIS
EU research results

CORDIS

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Inhalable Aerosol Light Source for Controlling Drug-Resistant Bacterial Lung Infections

Project information

Grant agreement ID: 863102

Status

Ongoing project

  • Start date

    1 December 2019

  • End date

    30 November 2023

Funded under:

H2020-EU.1.2.1.

  • Overall budget:

    € 3 493 625

  • EU contribution

    € 3 493 625

Coordinated by:

INSTITUT QUIMIC DE SARRIA

Spain

Project description

English EN

Novel treatment of drug-resistant bacterial lung infections

The growing resistance to many antibiotics and the emergence of multidrug-resistant bacteria calls for the development of alternative antibacterial therapies. Currently, bacterial drug resistance is the leading cause of morbidity and mortality in patients with cystic fibrosis and hospital-acquired lung infections. The EU-funded project will develop new treatment for bacterial lung infections using inhalable light sources that excite bacterial endogenous photosensitisers (porphyrins), killing the bacteria via the photodynamic effect (local production of reactive cytotoxic oxygen). The treatment will be safe for host tissues and effective against drug-resistant pathogens. Research involves the development of inhalable luminescent particles, the method for delivery to the lungs, and evaluation of the treatment parameters in relevant clinical models.

Coordinator

INSTITUT QUIMIC DE SARRIA

Address

Calle Via Augusta 384-394
08017 Barcelona

Spain

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 714 375

Participants (7)

UNIVERSITA DEGLI STUDI DI FIRENZE

Italy

EU Contribution

€ 593 125

SORBONNE UNIVERSITE

France

EU Contribution

€ 294 250

FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA

Spain

EU Contribution

€ 372 500

UNIVERSITA DEGLI STUDI DI PADOVA

Italy

EU Contribution

€ 410 000

CARDIFF SCINTIGRAPHICS LIMITED

United Kingdom

EU Contribution

€ 336 875

THE UNIVERSITY OF LIVERPOOL

United Kingdom

EU Contribution

€ 532 500

WEDO PROJECT INTELLIGENCE MADE EASY SL

Spain

EU Contribution

€ 240 000

Project information

Grant agreement ID: 863102

Status

Ongoing project

  • Start date

    1 December 2019

  • End date

    30 November 2023

Funded under:

H2020-EU.1.2.1.

  • Overall budget:

    € 3 493 625

  • EU contribution

    € 3 493 625

Coordinated by:

INSTITUT QUIMIC DE SARRIA

Spain