Mechanobiologically mimetic model systems for study of Bone disease (MEMETic)

Project Information

MEMETic

Grant agreement ID: 863795

DOI

10.3030/863795

EC signature date 6 April 2020

Start date 1 September 2020

End date 31 August 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 999 956,00

EU contribution

€ 1 999 956,00

Coordinated by

UNIVERSITY OF GALWAY
Ireland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Publications

Peer reviewed articles (6)

A mechanobiological model of bone metastasis reveals that mechanical stimulation inhibits the pro-osteolytic effects of breast cancer cells

Author(s): Vatsal Kumar, Syeda M. Naqvi, Anneke Verbruggen, Eoin McEvoy, Laoise M. McNamara
Published in: Cell Reports, Issue 43, 2025, Page(s) 114043, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2024.114043

Altered extracellular matrix and mechanotransduction gene expression in rat bone tissue following long-term estrogen deficiency

Author(s): Syeda Masooma Naqvi, Laura M O’Sullivan, Hollie Allison, Vincent J Casey, Jessica Schiavi-Tritz, Laoise M McNamara
Published in: JBMR Plus, Issue 8, 2024, ISSN 2473-4039
Publisher: Oxford University Press (OUP)
DOI: 10.1093/jbmrpl/ziae098

Osteocytes and Estrogen Deficiency

Author(s): Laoise M. McNamara
Published in: Current Osteoporosis Reports, Issue 19, 2021, Page(s) 592-603, ISSN 1544-1873
Publisher: Current Science Inc.
DOI: 10.1007/s11914-021-00702-x

Temporal changes in cortical microporosity during estrogen deficiency associated with perilacunar resorption and osteocyte apoptosis: A pilot study

Author(s): H.Allison, L.M.O'Sullivan, L.M.McNamara
Published in: Bone Reports, 2022, ISSN 2352-1872
Publisher: Elsevier Inc.
DOI: 10.1016/j.bonr.2022.101590

Stem Cell Mechanobiology and the Role of Biomaterials in Governing Mechanotransduction and Matrix Production for Tissue Regeneration

Author(s): S. M. Naqvi, L. M. McNamara
Published in: Frontiers in Bioengineering and Biotechnology, Issue 8, 2022, ISSN 2296-4185
Publisher: Frontiers Media SA
DOI: 10.3389/fbioe.2020.597661

Estrogen deficiency alters vascularization and mineralization dynamics: insight from a novel 3-D humanized and vascularized bone organoid model

Author(s): Muhammad M. M. Bukhari, Mostafa Khabooshani, Syeda M. Naqvi, Laoise M. McNamara
Published in: American Journal of Physiology-Cell Physiology, Issue 328, 2025, Page(s) C743-C756, ISSN 0363-6143
Publisher: American Physiological Society
DOI: 10.1152/ajpcell.00738.2024

Book chapters (1)

Bone as a Material: Lessons From Nature.

Author(s): O’Sullivan, L.M., McNamara, L. M.
Published in: Encyclopedia of Materials: Technical Ceramics and Glasses, 2021, Page(s) 459–472
Publisher: Elsevier