(Photo-)Control of Persisters: Targeting the Magic Spot

Project Information

PP-MAGIC

Grant agreement ID: 864246

DOI

10.3030/864246

Project closed

EC signature date 22 January 2020

Start date 1 March 2020

End date 31 August 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Intracellular delivery and deep tissue penetration of nucleoside triphosphates using photocleavable covalently bound dendritic polycations

Author(s): Jiahui Ma, Johanna Wehrle, Dennis Frank, Lina Lorenzen, Christoph Popp, Wolfgang Driever, Robert Grosse, Henning J. Jessen
Published in: Chemical Science, Issue 15, 2024, Page(s) 6478-6487, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3sc05669d

Pools of Independently Cycling Inositol Phosphates Revealed by Pulse Labeling with ¹⁸O-Water

Author(s): Geun-Don Kim, Guizhen Liu, Danye Qiu, Maria Giovanna De Leo, Navin Gopaldass, Jacques Hermes, Jens Timmer, Adolfo Saiardi, Andreas Mayer, Henning Jacob Jessen
Published in: Journal of the American Chemical Society, Issue 147, 2025, Page(s) 17626-17641, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.4c16206

Absolute Quantitation of Inositol Pyrophosphates by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry

Author(s): Danye Qiu, Verena B. Eisenbeis, Adolfo Saiardi, Henning J. Jessen
Published in: Journal of Visualized Experiments, 2025, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/62847

Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry

Author(s): Danye Qiu, Miranda S. Wilson, Verena B. Eisenbeis, Robert K. Harmel, Esther Riemer, Thomas M. Haas, Christopher Wittwer, Nikolaus Jork, Chunfang Gu, Stephen B. Shears, Gabriel Schaaf, Bernd Kammerer, Dorothea Fiedler, Adolfo Saiardi, Henning J. Jessen
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-19928-x

ESIPT fluorescence turn-on sensors for detection of short chain inorganic polyphosphate in water

Author(s): Subhra Kanti Roy, Sandra Moser, Tobias Dürr-Mayer, Rahel Hinkelmann, Henning J. Jessen
Published in: Organic & Biomolecular Chemistry, Issue 23, 2025, Page(s) 1373-1379, ISSN 1477-0520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4ob01926a

The aryne phosphate reaction

Author(s): Thomas M. Haas, Stefan Wiesler, Tobias Dürr-Mayer, Alexander Ripp, Paraskevi Fouka, Danye Qiu, Henning Jacob Jessen
Published in: Angewandte Chemie International Edition, 2021, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202113231

Four Phosphates at One Blow: Access to Pentaphosphorylated Magic Spot Nucleotides and Their Analysis by Capillary Electrophoresis

Author(s): Thomas M. Haas, Danye Qiu, Markus Häner, Larissa Angebauer, Alexander Ripp, Jyoti Singh, Hans-Georg Koch, Claudia Jessen-Trefzer, Henning J. Jessen
Published in: The Journal of Organic Chemistry, Issue 85/22, 2020, Page(s) 14496-14506, ISSN 0022-3263
Publisher: American Chemical Society
DOI: 10.1021/acs.joc.0c00841

Bacterial Pathogen Infection Triggers Magic Spot Nucleotide Signaling in <i>Arabidopsis thaliana</i> Chloroplasts through Specific RelA/SpoT Homologues

Author(s): Danye Qiu, Esther Lange, Thomas M. Haas, Isabel Prucker, Shinji Masuda, Yan L. Wang, Georg Felix, Gabriel Schaaf, Henning J. Jessen
Published in: Journal of the American Chemical Society, Issue 145, 2023, Page(s) 16081-16089, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.3c04445

Stable isotope phosphate labelling of diverse metabolites is enabled by a family of 18O‐phosphoramidites

Author(s): Thomas M. Haas, Stephan Mundinger, Danye Qiu, Nikolaus Jork, Kevin Ritter, Tobias Dürr-Mayer, Alexander Ripp, Adolfo Saiardi, Gabriel Schaaf, Henning Jacob Jessen
Published in: Angewandte Chemie, 2021, ISSN 0044-8249
Publisher: Wiley
DOI: 10.1002/ange.202112457

Photoaffinity capture compounds to profile the Magic Spot Nucleotide interactomes

Author(s): Thomas M. Haas; Benoît‐Joseph Laventie; Simon Lagies; Caroline Harter; Isabel Prucker; Danilo Ritz; Raspudin Saleem‐Batcha; Danye Qiu; Wolfgang Hüttel; Jennifer Andexer; Bernd Kammerer; Urs Jenal; Henning J. Jessen
Published in: Angewandte Chemie Int. Ed., Issue 1, 2022, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202201731

The P(III)‐Amidite Based Synthesis of Stable Isotope Labeled mRNA‐Cap‐Structures Enables their Sensitive Quantitation from Brain Tissue

Author(s): Alexander Ripp, Martina Krämer, Vanessa Barth, Patrick Moser, Thomas M. Haas, Jyoti Singh, Tamara Huck, Lukas Gleue, Kristina Friedland, Mark Helm, Henning J. Jessen
Published in: Angewandte Chemie International Edition, Issue 64, 2025, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202414537

Non-peer reviewed articles (2)

Controlled Delivery and Light-Induced Release of Magic Spot Nucleotides in Escherichia coli

Author(s): Christoph Popp, Patrick Moser, Xinwei H. Liu, Johannes Freitag, Isabel Prucker, Robert Zscherp, Xuan Wang, Philipp Klahn, Hans-Georg Koch, Gert Bange, Henning J. Jessen
Published in: Biorxiv, 2025, ISSN 2692-8205
Publisher: Openrxiv
DOI: 10.1101/2025.10.22.683773

Bacterial Pathogen Infection Triggers Magic Spot Nucleotide Signaling in Arabidopsis thaliana Chloroplasts Through Specific RelA/SpoT Homologs

Author(s): Danye Qiu, Esther Riemer, Thomas M. Haas, Isabel Prucker, Shinji Masuda, Yan L. Wang, Georg Felix, Gabriel Schaaf, Henning J. Jessen
Published in: BioRxiv, 2023, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.04.26.538375

Other (1)

Waking up to a new era in antibiotics?

Author(s): Henning Jessen
Published in: 2022, ISSN 2752-4736
Publisher: Euresearch