Energizing microbes with redox mediators for new bioproductions

Project description

Redox mediators in bioproductions

Currently, a broad bioproduct portfolio in many bioprocesses can only be achieved when microorganisms have access to oxygen as an electron acceptor. However, for many target substances, oxygen is harmful to the operation of the bioprocess and for product stability. The central goal of the EU-funded e-MICROBe project is to couple microbial metabolism and electrochemistry via a self-secreted soluble electron mediator to achieve efficient oxygen-independent energy metabolism and directly control metabolism and product formation. The project will evaluate an all-in-one strategy, where one cell is generating the mediators and the targeted product, and the alternative approach of a co-culture system, where one cell produces the mediators and a partner cell utilises them for electro-respiration and product formation.

Field of science

/natural sciences/biological sciences/microbiology
/engineering and technology/industrial biotechnology/biomaterials

Funding Scheme

ERC-COG - Consolidator Grant

Host institution

LEIBNIZ-INSTITUT FUR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE EV HANS-KNOLL-ISTITUT

Address

Beutenberg Strasse 11A
07745 Jena
Germany

Activity type

Research Organisations

EU contribution

€ 1 999 991

Website

Contact the organisation

Beneficiaries (1)

LEIBNIZ-INSTITUT FUR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE EV HANS-KNOLL-ISTITUT

Germany