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Evolutionary Consequences of Arrested Genomic Conflict in Asexual Species

Project description

What motivates selfish genes when sex is off the table

Internal conflict takes on new meaning when it comes to genes. So-called selfish genetic elements are self-promoting, enhancing their own transmission relative to the rest of the organism's genome despite having neutral or harmful effects. Both intergenomic and intragenomic conflicts exist. The former relate to differential effects based on the carrier, such as whether they are passed to males or females. The fitness consequences can be sexually antagonistic, whereby genetic variations favourable in one sex are harmful to the other. The EU-funded No Sex No Conflict project is teasing apart inter- versus intragenomic conflict and their role in genotypic and phenotypic evolution via a study of asexual stick insect species in which sexual conflict over optimal trait values disappears. Given that genomic conflicts play an increasingly recognised role in human disease, insights could help us understand these processes better.

Call for proposal

ERC-2019-COG
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Funding Scheme

ERC-COG - Consolidator Grant

Host institution

UNIVERSITE DE LAUSANNE
Address
Quartier Unil-centre Bâtiment Unicentre
1015 Lausanne
Switzerland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 989 769

Beneficiaries (1)

UNIVERSITE DE LAUSANNE
Switzerland
EU contribution
€ 1 989 769
Address
Quartier Unil-centre Bâtiment Unicentre
1015 Lausanne
Activity type
Higher or Secondary Education Establishments