Reconstructing the coordinated self-assembly of a bacterial nanomachine

Project Information

BacNanoMachine

Grant agreement ID: 864971

DOI

10.3030/864971

EC signature date 16 April 2020

Start date 1 October 2020

End date 30 September 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 934 950,00

EU contribution

€ 1 934 950,00

Coordinated by

HUMBOLDT-UNIVERSITAET ZU BERLIN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (13)

Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit

Author(s): Hu, Haidai; Popp, Philipp F.; Santiveri, Mònica; Roa-Eguiara, Aritz; Yan, Yumeng; Martin, Freddie J. O.; Liu, Zheyi; Wadhwa, Navish; Wang, Yong; Erhardt, Marc; Taylor, Nicholas M. I.
Published in: Nature Communications, Issue 14(1), 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-39899-z

SPI-1 virulence gene expression modulates motility of Salmonella Typhimurium in a proton motive force- and adhesins-dependent manner

Author(s): Doaa Osama Saleh; Julia A. Horstmann; María Giralt-Zúñiga; Willi Weber; Eugen Kaganovitch; Abilash Chakravarthy Durairaj; Enrico Klotzsch; Till Strowig; Marc Erhardt
Published in: PLOS Pathogens, Issue 2, 2023, ISSN 1553-7366
Publisher: Public Library of Science
DOI: 10.1371/journal.ppat.1011451

Fluorescent tools for the standardized work in Gram-negative bacteria

Author(s): Mario Delgadillo-Guevara, Manuel Halte, Marc Erhardt, Philipp F. Popp
Published in: Journal of Biological Engineering, Issue 18, 2024, ISSN 1754-1611
Publisher: BioMed Central
DOI: 10.1186/s13036-024-00420-9

BldD‐based bimolecular fluorescence complementation for in vivo detection of the second messenger cyclic di‐GMP

Author(s): Manuel Halte; Mirka E. Wörmann; Maxim Bogisch; Marc Erhardt; Natalia Tschowri
Published in: Molecular Microbiology, Issue 1, 2022, ISSN 0950-382X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/mmi.14876

A guide for membrane potential measurements in Gram-negative bacteria using voltage-sensitive dyes.

Author(s): Buttress, JA; Halte, M; Te Winkel, JD; Erhardt, M; Popp, PF; Strahl, H
Published in: Microbiology (Reading), Issue 168(9), 2022, ISSN 1350-0872
Publisher: Society for General Microbiology
DOI: 10.1099/mic.0.001227

Bacterial motility depends on a critical flagellum length and energy-optimized assembly

Author(s): Manuel Halte, Philipp F. Popp, David Hathcock, John Severn, Svenja Fischer, Christian Goosmann, Adrien Ducret, Emmanuelle Charpentier, Yuhai Tu, Eric Lauga, Marc Erhardt, Thibaud T. Renault
Published in: Proceedings of the National Academy of Sciences, Issue 122, 2025, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2413488122

Control of membrane barrier during bacterial type-III protein secretion.

Author(s): Hüsing, S; Halte, M; van Look, U; Guse, A; Gálvez, EJC; Charpentier, E; Blair, DF; Erhardt, M; Renault, TT
Published in: Nature Communications, Issue 1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24226-1

The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation

Author(s): Rosa Einenkel, Kailin Qin, Julia Schmidt, Natalie S. Al-Otaibi, Daniel Mann, Tina Drobnič, Eli J. Cohen, Nayim Gonzalez-Rodriguez, Jane Harrowell, Elena Shmakova, Morgan Beeby, Marc Erhardt, Julien R. C. Bergeron
Published in: Nature Microbiology, Issue 10, 2025, Page(s) 1741-1757, ISSN 2058-5276
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41564-025-02037-0

Protein Export via the Type III Secretion System of the Bacterial Flagellum

Author(s): Halte, M; Erhardt, M
Published in: Biomolecules, Issue 1, 2021, ISSN 2218-273X
Publisher: MDPI
DOI: 10.3390/biom11020186

Structure and mechanism of the Zorya anti-phage defence system

Author(s): Haidai Hu, Philipp F. Popp, Thomas C. D. Hughes, Aritz Roa-Eguiara, Nicole R. Rutbeek, Freddie J. O. Martin, Ivo Alexander Hendriks, Leighton J. Payne, Yumeng Yan, Dorentina Humolli, Victor Klein-Sousa, Inga Songailiene, Yong Wang, Michael Lund Nielsen, Richard M. Berry, Alexander Harms, Marc Erhardt, Simon A. Jackson, Nicholas M. I. Taylor
Published in: Nature, Issue 639, 2025, Page(s) 1093-1101, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-024-08493-8

Hook-basal body assembly state dictates substrate specificity of the flagellar type-III secretion system

Author(s): Alina Guse; Alina Guse; Manuel Halte; Svenja Hüsing; Marc Erhardt
Published in: Molecular Microbiology, Issue 1, 2021, ISSN 0950-382X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/mmi.14805

FlhE functions as a chaperone to prevent formation of periplasmic flagella in Gram-negative bacteria

Author(s): Manuel Halte, Ekaterina P. Andrianova, Christian Goosmann, Fabienne F. V. Chevance, Kelly T. Hughes, Igor B. Zhulin, Marc Erhardt
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-50278-0

A versatile regulatory toolkit of arabinose-inducible artificial transcription factors for Enterobacteriaceae

Author(s): Naseri, Gita; Raasch, Hannah; Charpentier, Emmanuelle; Erhardt, Marc
Published in: Communications Biology, Issue 6(1), 2023, ISSN 2399-3642
Publisher: Springer Nature, 2018-
DOI: 10.1038/s42003-023-05363-3

Book chapters (1)

Quantifying Substrate Protein Secretion via the Type III Secretion System of the Bacterial Flagellum Bacterial Secretion Systems : Methods and Protocols

Author(s): Einenkel, Rosa; Halte, Manuel; Erhardt, Marc
Published in: Methods in Molecular Biology, 2023, ISBN 978-1-0716-3445-5
Publisher: Humana, New York, NY
DOI: 10.1007/978-1-0716-3445-5_36

Non-peer reviewed articles (1)

Supercoiled filaments propel them all

Author(s): Popp, Philipp F.; Erhardt, Marc
Published in: Cell, Issue 185(19), 2022, Page(s) 3461-3463, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2022.08.016