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Resurrecting the Carboxyl Polyether Ionophores


Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro

Author(s): Esben B. Svenningsen, Jacob Thyrsted, Julia Blay-Cadanet, Han Liu, Shaoquan Lin, Jaime Moyano-Villameriel, David Olagnier, Manja Idorn, Søren R. Paludan, Christian K. Holm, Thomas B. Poulsen
Published in: Antiviral Research, Issue 185, 2021, Page(s) 104988, ISSN 0166-3542
Publisher: Elsevier BV
DOI: 10.1016/j.antiviral.2020.104988

Total Synthesis of Natural Products Containing Enamine or Enol Ether Derivatives

Author(s): Thomas B. Poulsen
Published in: Accounts of Chemical Research, Issue 54/8, 2021, Page(s) 1830-1842, ISSN 0001-4842
Publisher: American Chemical Society
DOI: 10.1021/acs.accounts.0c00851

Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity-focused semisynthesis

Author(s): Shaoquan Lin, Han Liu, Esben B. Svenningsen, Malene Wollesen, Kristian M. Jacobsen, Frederikke D. Andersen, Jaime Moyano-Villameriel, Christine N. Pedersen, Peter Nørby, Thomas Tørring, Thomas B. Poulsen
Published in: Nature Chemistry, Issue 13/1, 2021, Page(s) 47-55, ISSN 1755-4330
Publisher: Nature Publishing Group
DOI: 10.1038/s41557-020-00601-1

α-Lactam Electrophiles for Covalent Chemical Biology

Author(s): Alejandro Mahía, Anders E. Kiib, Marija Nisavic, Esben B. Svenningsen, Johan Palmfeldt, Thomas B. Poulsen
Published in: Angewandte Chemie International edition, 2023, ISSN 1521-3773
Publisher: Wiley-VCH GmbH
DOI: 10.1002/anie.202304142

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