Resurrecting the Carboxyl Polyether Ionophores

Project Information

RECYPION

Grant agreement ID: 865738

DOI 10.3030/865738

EC signature date 19 February 2020

Start date 1 March 2020

End date 31 August 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 998 864,00

EU contribution € 1 998 864,00

Coordinated by

AARHUS UNIVERSITET
Denmark

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

The Biological Activities of Polyether Ionophore Antibiotic Routiennocin is Independent of Absolute Stereochemistry

Author(s): Søren Lau Borcher Møller, Michelle H. Rasmussen, Jun Li, Esben B. Svenningsen, Gustav J. Wørmer, Thomas Tørring, Thomas B. Poulsen
Published in: ChemBioChem, Issue 25, 2024, Page(s) e202400013, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202400013

Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro

Author(s): Esben B. Svenningsen, Jacob Thyrsted, Julia Blay-Cadanet, Han Liu, Shaoquan Lin, Jaime Moyano-Villameriel, David Olagnier, Manja Idorn, Søren R. Paludan, Christian K. Holm, Thomas B. Poulsen
Published in: Antiviral Research, Issue 185, 2021, Page(s) 104988, ISSN 0166-3542
Publisher: Elsevier BV
DOI: 10.1016/j.antiviral.2020.104988

Polyether Ionophore Antibiotics Target Drug-Resistant Clinical Isolates, Persister Cells, and Biofilms

Author(s): Malene Wollesen, Kasper Mikkelsen, Marie Selch Tvilum, Martin Vestergaard, Mikala Wang, Rikke L. Meyer, Hanne Ingmer, Thomas B. Poulsen, Thomas Tørring
Published in: Microbiology Spectrum, Issue 11, 2023, Page(s) e00625-23, ISSN 2165-0497
Publisher: ASM Journals
DOI: 10.1128/spectrum.00625-23

Total Synthesis of Natural Products Containing Enamine or Enol Ether Derivatives

Author(s): Thomas B. Poulsen
Published in: Accounts of Chemical Research, Issue 54/8, 2021, Page(s) 1830-1842, ISSN 0001-4842
Publisher: American Chemical Society
DOI: 10.1021/acs.accounts.0c00851

Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity-focused semisynthesis

Author(s): Shaoquan Lin, Han Liu, Esben B. Svenningsen, Malene Wollesen, Kristian M. Jacobsen, Frederikke D. Andersen, Jaime Moyano-Villameriel, Christine N. Pedersen, Peter Nørby, Thomas Tørring, Thomas B. Poulsen
Published in: Nature Chemistry, Issue 13/1, 2021, Page(s) 47-55, ISSN 1755-4330
Publisher: Nature Publishing Group
DOI: 10.1038/s41557-020-00601-1

α-Lactam Electrophiles for Covalent Chemical Biology

Author(s): Alejandro Mahía, Anders E. Kiib, Marija Nisavic, Esben B. Svenningsen, Johan Palmfeldt, Thomas B. Poulsen
Published in: Angewandte Chemie International edition, 2023, ISSN 1521-3773
Publisher: Wiley-VCH GmbH
DOI: 10.1002/anie.202304142