Novel compounds remove the cloak of antibiotic resistance from deadly bacteria
Gram-positive bacteria account for about 60 % of respiratory, intra-abdominal and urinary tract infections. They include Staphylococcus aureus and Enterococci, both leading causes of endocarditis and hospital-acquired illnesses – both forming highly virulent antibiotic-resistant strains. Scientists have been working hard to come up with new weapons against these predators. Now, QTB4AMR may have found one. Rather than develop new drugs, the project has developed compounds that restore antibiotic sensitivity in methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Their simple and elegant solution will potentially stop these serial killers in their tracks and simultaneously preserve the huge global investment that was devoted to bringing these conventional antibiotics to market.
Fields of science
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