Project description
Preventing plant diseases by vector modification strategies
The rising global population puts constant pressure on food production and intensive agricultural practices. Alongside the injudicious use of insecticides, this has modified agrarian ecosystems, causing more plant vector-borne viral diseases than ever before. The EU-funded GuardSym project will focus on the whitefly Bemisia tabaci as a vector to investigate its multitrophic interactions with its bacterial symbionts, vectored virus, and host plants. Scientists will employ a multidisciplinary approach that combines insect and plant physiology, virology, and high-throughput sequencing to identify symbionts that confer virus-resistance to their whitefly host. The project will form the basis for the development of population modification strategies where natural populations are replaced with virus-resistant ones that can no longer cause plant disease.
Objective
Agriculture is facing constant pressure to increase food production to fulfill human population demands. This has been accomplished by the use of intensive agricultural techniques. The increase of global temperatures together with intensive techniques like worldwide movements of plant material, use of monocultures, and abuse on insecticides have modified the trophic chains in agricultural systems. As a consequence, there is an unprecedented increase in emergent plant viral diseases in the last decades. Most of these viruses require an insect vector for their transmission. Unfortunately, some vector insects have been favored by intensive agriculture. Indeed, the whitefly Bemisia tabaci has become a worldwide supervector and is the cause of the global emergence of begomoviruses and criniviruses. This whitefly has developed resistance to many insecticides and developing new control techniques is a must. Recently, a population modification strategy has been applied to mosquitoes, displacing natural populations and replacing them with virus-resistant ones that are no longer able to transmit human diseases. This success has been achieved using Wolbachia, a bacterial symbiont present in many insects, that can confer virus-resistance phenotypes to its host. Interestingly, B. tabaci presents a rich bacterial symbiotic community, including Wolbachia, that can be naturally manipulated through hybridization. This offers the unique opportunity to unravel the multitrophic interactions that occur between B. tabaci, its symbionts, the vectored virus, and the plant. Using integrative frameworks to study the insect and the plant physiology, the virus transmission, the symbionts dynamics, and the cross-talks between them (their transcriptomes) can lead to the discovery of new symbiotic virus-resistant phenotypes in B. tabaci. If this is achieved, it will be a keystone to develop further population modification strategies to spread symbionts conferred virus-resistances.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology virology
- natural sciences biological sciences genetics RNA transcriptomes
- agricultural sciences agriculture, forestry, and fisheries agriculture
- natural sciences biological sciences zoology entomology
- natural sciences biological sciences zoology invertebrate zoology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2019
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75794 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.