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TRANSLATION INITIATION CONTROL IN PLANTS: THE ROLE OF TOR (TARGET OF RAPAMYCIN)

Project description

Dissecting gene regulation in plants

Regulation of gene expression in eukaryotes is fundamental for cell survival, differentiation and development. Regulation at the protein synthesis stage is critical and involves the target of rapamycin (TOR) protein kinase, which suppresses the function of translation repressor proteins. To achieve this, the TOR signalling pathway integrates nutrient and energy sufficiency information as well as hormone and growth factor levels. The EU-funded TOR in acTIon project has set out to understand how plants employ TOR to regulate protein synthesis. The key objective is to identify regulatory factors that function under the control of TOR in translation initiation and to decipher the role of the plant hormone auxin, a key coordinator of plant growth.

Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Net EU contribution
€ 184 707,84
Address
Rue Michel Ange 3
75794 Paris
France

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 0,00