Project description
A new surgical guide to navigate in arteries
Stroke (cerebrovascular accident) is ranked as the second leading cause of accidental death worldwide with an annual mortality rate of about 5 million. Treatment includes endovascular radio-guided surgery in which the role of the guidewire is essential for navigating in arteries. However, it is not easy to properly direct and manage the guidewire, requiring surgeons to remove it and reshape the tip by hand. The results are are a loss of time, increased risk of infection and higher costs. The EU-funded SmartGUIDE project is developing an innovative guidewire that contains a remotely-shapeable tip that allows the surgeon to change the shape of the instrument’s head while navigating through brain arteries. This innovative device, which is compatible with existing endovascular instruments, will significantly reduce surgery time and costs.
Objective
Each year, 15 million people suffer from stroke, resulting in 5 million deaths worldwide. This disease is treated via endovascular radio-guided surgery, where the guidewire used to navigate in arteries to reach a lesion is very difficult to orient and steer. At least 5 times per surgery, the surgeon has no choice but to remove the guidewire and reshape the tip by hand, a poorly controlled procedure. This results in increased infection and artery puncture risk for the patient, longer surgery duration (by 30 minutes) and higher costs.
A total of 232’000 neuro-endovascular procedures are carried out in the US and EU to prevent and treat haemorrhagic and ischemic strokes. This represents a directly addressable market of €390M for SmartGUIDE. This market is a rapidly expanding sector with an estimated CAGR of 8.6% (2016 – 2021).
Artiria Medical is a Swiss Spin-off from the EPFL founded in 2017 with the vision to bring disruptive minimally invasive technologies to physicians in order to decrease Stroke mortality and improve the patient’s quality of life. Our first product SmartGUIDE, is the next generation guidewire which comprises a unique remotely-shapeable tip, developed in collaboration with renowned specialists in the field of interventional neuroradiology. This patented innovation allows the surgeon to deflect in real-time, using a manipulator handle, the device head while navigating through brain arteries, making it easy to use with no training required.
SmartGUIDE thus saves 30 minutes per surgery. Saving time translates to a direct improvement of patient recovery. SmartGUIDE replaces on average 2 devices for each procedure, thus reducing the overall surgery cost by €1,200 and is fully compatible with existing endovascular devices.
Artiria is expected to generate 35 new jobs, annual revenue of €29.32M and cummulative profit of €18.32 by the 5th year of commercialization with a ROI of 7.4. Breakeven will be achieved by the 3rd year of commercialization.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences sociology demography mortality
- medical and health sciences clinical medicine surgery
- medical and health sciences basic medicine neurology stroke
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1277 BOREX
Switzerland
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.