Unraveling fish brains with in vivo optical imaging and advanced mathematical modelling
Understanding the behaviour of organisms like ourselves that integrate environmental cues and neural stimuli with cognitive processing is a very complex task. Harnessing the power of simple-model organisms such as the zebrafish together with the power of computational analytical methods could enable the characterisation of complex brain-body-environment interactions in living organisms. Zebrafish share many major organs and tissues with humans, and larval zebrafish are optically transparent, facilitating the in vivo imaging of calcium dynamics during nervous system activation. The EU-funded DIMENSIVE project is recording the neural activity of behaving zebrafish and using the data to develop generative models of large-scale behaviour. The advanced statistical models will allow scientists to create new data instances, providing important insight into how behaviour arises from the dynamical interaction of an organism’s nervous system, body and environment.
Fields of science
- natural sciencesbiological sciencesneurobiologycognitive neuroscience
- natural sciencesmathematicsapplied mathematicsstatistics and probabilitybayesian statistics
- natural sciencesphysical sciencesclassical mechanicsstatistical mechanics
- natural sciencescomputer and information sciencessoftwaresoftware applicationsvirtual reality
- natural sciencesbiological sciencesbiological behavioural sciencesethology