The role of ciliary tip organization in hedgehog signaling

Project description

Ciliary tip organisation in hedgehog signalling

Eukaryotic cells are strewn with slender protuberances called cilia organelles, which have essential motile, sensory and signalling functions. The cilium structure is important for its function; the mechanisms underlying the relationship between structure and function, however, are not well understood. The EU-funded CiliaryTip project aims to address the role of the cilium structure in hedgehog signalling, one of the main cilia-based signalling pathways, essential for embryonic development and implicated in disease. This work will impact how hedgehog-related diseases are examined in the future, generating insights with broader implications regarding the signalling and sensory roles of cilia.

Fields of science

• natural sciences › biological sciences › biochemistry › biomolecules › proteins
• natural sciences › biological sciences › developmental biology
• natural sciences › biological sciences › zoology › mammalogy

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2019 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2019

See other projects for this call

Funding Scheme

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

Coordinator

UNIVERSITY OF CYPRUS

Net EU contribution

€ 145 941,12

Address

Avenue Panepistimiou 2109 Aglantzi
1678 Nicosia
Cyprus

Region

Κύπρος › Κύπρος › Κύπρος

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00