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Quantification of Free and Bound Water Concentrations in Human Cortical Bone Employing Hybrid Hard-tissue MRI: Towards Comprehensive Osteoporosis Assessment

Project description

Bone water imaging for the diagnosis of osteoporosis

Osteoporosis weakens bones, causing millions of fractures in the world every year. Bone quality is usually assessed through the bone mineralisation process, which however offers an incomplete view on the quality of the bone. The EU-funded ROCHESTER project proposes to utilise water content, a richer source of information on bone porosity. Researchers will develop a novel diagnostic technique based on magnetic resonance imaging (MRI) to generate quantitative imaging biomarkers associated with cortical bone free and bound water concentrations. The project has the potential to improve the diagnosis of osteoporosis and the assessment of bone development in paediatrics, reducing the economic burden on healthcare systems.

Coordinator

UNIVERSITY OF LEEDS
Net EU contribution
€ 224 933,76
Address
Woodhouse Lane
LS2 9JT Leeds
United Kingdom

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Region
Yorkshire and the Humber West Yorkshire Leeds
Activity type
Higher or Secondary Education Establishments
Other funding
€ 224 933,76