Objective
Low absorption differences, leading to poor image contrast, are one of the main limitations in diagnostic radiology. This is particularly relevant in the field of mammography, where the detection of small nodules, which would result in an early detection of the disease with consequent reduction of the mortality rate, is severely affected by this limitation.
It has been demonstrated that phase contrast imaging, an innovative technique based on phase effects, has the potential of removing to a large extent this limitation, and thus of pushing forward the state-of-the-art of diagnostic radiology. The aim of the present project is the clinical implementation of phase contrast imaging.
The technique has been developed mainly in synchrotron radiation environments, which has prevented its widespread application despite the extremely high potentials: the application of the technique is in fact limited by the necessity of a high coherence in the x-ray source, as well as by the requirement of a high detector spatial re solution.
Provided that source-to-sample and source-to-detector distances are optimised, modern, high power micro-focal x-ray sources are capable of providing enough coherence: several studies have demonstrated that, while a high spatial coherence is strictly necessary, the requirements on temporal (chromatic) coherence are much more relaxed.
In addition, I recently developed, in the framework of a synchrotron radiation experiment, a technique capable of removing the limitations on the detector spatial resolution, based on the design of specific slit systems. By precisely characterizing a micro-focal source and a flat panel detector, the above technique would enable the design of set-up suited to the specific source-detector combination.
This would allow the realization of a prototype for clinical phase contrast imaging, which would have the potentials of improving, to an extent that would be carefully estimated, the state-of-the-art of diagnostic radiology.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences sociology demography mortality
- medical and health sciences clinical medicine radiology
- medical and health sciences clinical medicine oncology breast cancer
- natural sciences mathematics applied mathematics mathematical model
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-5
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
LONDON
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.