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Single-cell nuclear magnetic resonance spectroscopy with diamond quantum sensors

Project description

A novel quantum sensor-based NMR tool for studying single cells

To understand biological phenomena, scientists often study mixed-cell populations. However, cell heterogeneity may mask characteristics that emerge from single cells, necessitating the development of single-cell technologies. Nuclear magnetic resonance (NMR) spectroscopy is a key analytical tool that offers high molecular specificity in a non-invasive manner, but its low sensitivity renders it unsuitable for single-cell studies. The EU-funded SingleCellQNMR project is based on a recently developed diamond quantum sensing technique that allows the detection of NMR signals from tiny volumes, such as from a single cell. Using this technology, scientists plan to analyse and quantify metabolites at the single-cell level over time.

Call for proposal

ERC-2020-STG
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Host institution

TECHNISCHE UNIVERSITAET MUENCHEN
Address
Arcisstrasse 21
80333 Muenchen
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 120 290

Beneficiaries (1)

TECHNISCHE UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 2 120 290
Address
Arcisstrasse 21
80333 Muenchen
Activity type
Higher or Secondary Education Establishments