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Advanced hybrid theranostic nanoplatforms for an active drug delivery in the cancer treatment

Project description

Research consortium for the development of therapeutic and diagnostic nanostructures

Combination therapy in cancer, based on the simultaneous administration of several pharmacological agents with different modes of action using nanocarriers for the delivery, represents an effective treatment strategy. The nanostructured materials enable efficient drug delivery and high sensitivity in diagnostics. The EU-funded NANO4TARMED project will help establish a consortium of three research institutions in Czechia, Italy and Ireland for the creation of a scientific cluster promoting research and development through a set of workshops, seminars and extensive exchange of early-stage researchers. The consortium will aim to develop functional 3D dual-modality nanostructures for targeted therapeutic drug delivery and cell imaging.

Objective

Cancer is one of the leading causes of death worldwide. Great efforts are still necessary to individuate new therapeutic strategies aimed to reduce cancer recurrence and to define new potential adjuvant targets for inhibiting invasion and metastasis, two significant contributors to death among patients. The combination therapy based on the simultaneous administration of two or more pharmacologically active agents with different modes of action using nanocarriers for the delivery could represent an effective strategy for the treatment. The increase in efficacy of a therapeutic formulation is causally related to its ability to selectively target diseased tissue, overcome biological barriers, and smartly respond to the disease environment to release therapeutic agents. The increasing interest in the employment of nanostructured materials to medicine-related branches is attributable to its unique properties allowing highly efficient drug delivery, molecular sensing applicable in diagnosis, multiplex imaging, or construction of point of care therapeutic devices. This project aims at an establishment of a consortium consisted of Regional centre of advanced technologies and materials (part of Palacký University), The Institute of Science and Technology for Ceramics (part of CNR) and Maynooth University which will through a set of workshops, seminars and extensive exchange of early-stage researchers develop an efficient scientific cluster. The research of the cluster will aim the development of functional 3D dual-modality nanostructures for targeted drug delivery and cell imaging.

Call for proposal

H2020-WIDESPREAD-2018-2020

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Sub call

H2020-WIDESPREAD-2020-5

Coordinator

UNIVERZITA PALACKEHO V OLOMOUCI
Net EU contribution
€ 401 218,75
Address
KRIZKOVSKEHO 8
771 47 Olomouc
Czechia

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Region
Česko Střední Morava Olomoucký kraj
Activity type
Higher or Secondary Education Establishments
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Total cost
€ 401 218,75

Participants (2)