Game-changing uPAR-targeting dye for guiding surgical treatment of cancer

Project Information

INSTAGLOW

Grant agreement ID: 954904

DOI

10.3030/954904

Project closed

EC signature date 5 June 2020

Start date 1 July 2020

End date 31 December 2022

Funded under

• INDUSTRIAL LEADERSHIP - Innovation In SMEs

Total cost

€ 5 085 250,50

EU contribution

€ 2 499 868,69

Coordinated by

FLUOGUIDE AS
Denmark

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (2)

Publication of initial clinical result
Publication of clinical trial metrology

Publications

Peer reviewed articles (2)

IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts

Author(s): Sorel Kurbegovic, Karina Juhl, Kasper Kildegaard Sørensen, Julie Leth, Gro Linno Willemoe, Anders Christensen, Yvonne Adams, Anja Ramstedt Jensen, Christian von Buchwald, Jane Skjøth-Rasmussen, Michael Ploug, Knud J. Jensen, Andreas Kjaer
Published in: Theranostics, Issue 11/15, 2021, Page(s) 7159-7174, ISSN 1838-7640
Publisher: Ivyspring International Publisher
DOI: 10.7150/thno.49787

Urokinase-Type Plasminogen Activator Receptor (uPAR) PET/MRI of Prostate Cancer for Noninvasive Evaluation of Aggressiveness: Comparison with Gleason Score in a Prospective Phase 2 Clinical Trial

Author(s): Marie Øbro Fosbøl, Sorel Kurbegovic, Helle Hjorth Johannesen, Martin Andreas Røder, Adam Espe Hansen, Jann Mortensen, Annika Loft, Peter Meidahl Petersen, Jacob Madsen, Klaus Brasso, Andreas Kjaer
Published in: Journal of Nuclear Medicine, Issue 62/3, 2021, Page(s) 354-359, ISSN 0161-5505
Publisher: Kexue Chubaneshe/Science Press
DOI: 10.2967/jnumed.120.248120

Intellectual Property Rights

Patent (8)

A RECEPTOR-TARGETING CONJUGATE WITH AN EFFECTIVE PHARMACOKINETIC PROFILE

Application/Publication number: 20 20069991
Date: 2020-07-15
Applicant(s): FLUOGUIDE AS

uPAR-TARGETED PHOTOTHERMAL OPTICAL PROBES FOR PHOTOTHERMAL THERAPY

Application/Publication number: 20 20087653
Date: 2020-12-22
Applicant(s): FLUOGUIDE AS

UPAR TARGETING PEPTIDE FOR USE IN PEROPERATIVE OPTICAL IMAGING OF INVASIVE CANCER

Application/Publication number: 15 842107
Date: 2015-09-03
Applicant(s): FLUOGUIDE AS

UPAR TARGETING PEPTIDE FOR USE IN PEROPERATIVE OPTICAL IMAGING OF INVASIVE CANCER

Application/Publication number: 15 842107
Date: 2015-09-03
Applicant(s): FLUOGUIDE AS

uPAR-TARGETED PHOTOTHERMAL OPTICAL PROBES FOR PHOTOTHERMAL THERAPY

Application/Publication number: 20 20087653
Date: 2020-12-22
Applicant(s): FLUOGUIDE AS

A RECEPTOR-TARGETING CONJUGATE WITH AN EFFECTIVE PHARMACOKINETIC PROFILE

Application/Publication number: 20 20069991
Date: 2020-07-15
Applicant(s): FLUOGUIDE AS

A UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR-TARGETING PEPTIDE

Application/Publication number: 20 20070014
Date: 2020-07-15
Applicant(s): FLUOGUIDE AS

A UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR-TARGETING PEPTIDE

Application/Publication number: 20 20070014
Date: 2020-07-15
Applicant(s): FLUOGUIDE AS