Project description
Artificial synaptic input restoring sight
Age-related macular degeneration and retinitis pigmentosa are common eye diseases, caused by the degeneration of photoreceptors, which deprives bipolar cells (BCs) of light-dependent synaptic input. Treatment today is focused mainly on delaying vision loss. However, the neuronal damage affects only the presynaptic side of the synapse, while the possibility of activation of the denervated postsynaptic side remains preserved. Therefore, the EU-funded HyVIS project aims to combine several technologies to achieve the groundbreaking restoration of synaptic light-mediated input to BCs. It will conduct an artificial reproduction of basic processes responsible for the formation of the retinal image using an optically driven hybrid connection between a nano-sized neurotransmitter-releasing device and the denervated postsynaptic cell.
Fields of science
Programme(s)
Funding Scheme
RIA - Research and Innovation action
Coordinator
16163 Genova
Italy
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Participants (5)
5612 AE Eindhoven
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4056 Basel
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75006 Paris
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72074 Tuebingen
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8047 Zurich
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.