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Hybrid synapse for vision

Project description

Artificial synaptic input restoring sight

Age-related macular degeneration and retinitis pigmentosa are common eye diseases, caused by the degeneration of photoreceptors, which deprives bipolar cells (BCs) of light-dependent synaptic input. Treatment today is focused mainly on delaying vision loss. However, the neuronal damage affects only the presynaptic side of the synapse, while the possibility of activation of the denervated postsynaptic side remains preserved. Therefore, the EU-funded HyVIS project aims to combine several technologies to achieve the groundbreaking restoration of synaptic light-mediated input to BCs. It will conduct an artificial reproduction of basic processes responsible for the formation of the retinal image using an optically driven hybrid connection between a nano-sized neurotransmitter-releasing device and the denervated postsynaptic cell.

Call for proposal

H2020-FETOPEN-2018-2020

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Sub call

H2020-FETOPEN-2018-2019-2020-01

Coordinator

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Net EU contribution
€ 1 059 405,41
Address
Via Morego 30
16163 Genova
Italy

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Region
Nord-Ovest Liguria Genova
Activity type
Research Organisations
Other funding
€ 0,00

Participants (5)

TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands
Net EU contribution
€ 468 635,00
Address
Groene Loper 3
5612 AE Eindhoven

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Region
Noord-Brabant Zuidoost-Noord-Brabant
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
INSTITUT FUR MOLEKULARE UND KLINISCHE OPHTHALMOLOGIE BASEL
Switzerland
Net EU contribution
€ 187 170,84
Address
C/o Universitätsspital Basel, Augenklinik, Mittlere Strasse
4056 Basel

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Region
Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt
Activity type
Research Organisations
Other funding
€ 0,00
SORBONNE UNIVERSITE
France
Net EU contribution
€ 400 625,00
Address
21 Rue De L'ecole De Medecine
75006 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
EBERHARD KARLS UNIVERSITAET TUEBINGEN
Germany
Net EU contribution
€ 400 928,75
Address
Geschwister-scholl-platz
72074 Tuebingen

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Region
Baden-Württemberg Tübingen Tübingen, Landkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
MAXWELL BIOSYSTEMS AG
Switzerland
Net EU contribution
€ 418 537,50
Address
Albisriederstrasse 253
8047 Zurich

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00