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Engineered Conductive Proteins for Bioelectronics

Deliverables

Recombinant CTPR platform: e-Ps

Accomplishment of conductive structures based on engineered CTPR recombinant proteins BIOMA m12

Self-assembled conductive e-Ps-based fibers and biomaterials

Assembly of the engineered protein-based conductive modules into higher order structures: protein-based fibers and macroscopic biomaterials (BIOMA, m28)

Upscale production of e-Prots

Accomplishment of large-scale production of the engineered protein modules with conductive properties (BIOMA, m30)

Self-assembled conductive pCTPR (natural residues)

Accomplishment of conductive structures based on selfassembled engineered CTPR synthetic protein modules based fully on natural amino acids CiQUS m9

First screen of e-/H+ conducting e-Ps

Processing of conductive protein modules and accomplishment of efficient electron and proton conducting protein fibers and gel films BGU m18

Conductive properties at nano-fiber and gel-films

Determination of the conductive properties of the second generation of self-assembled nanofibers and macroscopic gel-films composed of engineered conductive protein modules (BGU, m24)

Self-assembled pCTPR (artificial functionalities)

Accomplishment of conductive structures based on self-assembled engineered CTPR synthetic protein modules that include in their sequence non-natural amino acids (CiQUS, m24)

e/H+ transport properties of single e-Ps units

Characterization of the electron and proton transport features at the molecular level, using the designed conductive protein modules (UA, m24)

Publications

An Electroactive and Self-Assembling Bio-Ink, based on Protein-Stabilized Nanoclusters and Graphene, for the Manufacture of Fully Inkjet-Printed Paper-Based Analytical Devices

Author(s): Silvestri, A; Vázquez-Díaz, S; Misia, G; Poletti, F; López-Domene, R; Pavlov, V; Zanardi, C; Cortajarena, AL; Prato, M.
Published in: Small, Issue 19, 2023, Page(s) 2300163, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202300163

Engineering Proteins for PEDOT Dispersions: A New Horizon for Highly Mixed Ionic-Electronic Biocompatible Conducting Materials

Author(s): Dominguez-Alfaro, A.; Casado, N.; Fernandez, M.; Garcia-Esnaola, A.; Calvo, J.; Mantione, D.; Calvo, MR.; Cortajarena, AL
Published in: Small, Issue 2307536, 2023, Page(s) 2307536, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202307536

Molecular Graphene nanoribbon Junctions

Author(s): Mauro Marongiu, Tracy Ha, Sara Gil-Guerrero, Kavita Garg, Marcos Mandado, Manuel Melle-Franco, Ismael Diez-Perez, and Aurelio Mateo-Alonso
Published in: J. Am. Chem. Soc., Issue 146, 6,, 2024, Page(s) 3963–3973, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.3c11340

Crystallization of molecular layers produced under confinement onto a surface

Author(s): Jincheng Tong, Nathan de Bruyn, Adriana Alieva, Elizabeth. J. Legge, Matthew Boyes, Xiuju Song, Alvin J. Walisinghe, Andrew J. Pollard, Michael W. Anderson, Thomas Vetter, Manuel Melle-Franco & Cinzia Casiraghi
Published in: Nature Communications, Issue 15, 2024, Page(s) 2015, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-45900-0

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