Project description
Innovative material for faster drug development
Purification is key for all chemical industries. However, existing techniques are expensive, slow and inefficient in terms of energy consumption. This poses problems for health, safety and the environment. It’s also why purification represents an obstacle in drug discovery. The EU-funded SEP43 project will enter the market in drug discovery with a breakthrough multicapillary material that solves problems related to purification in the pharmaceutical and chemical industries. This disruptive technology decreases by an order of magnitude the operational pressure currently needed to separate molecules. Protected by six international patents, it is the first material to allow faster drug and chemical development at a lower cost, with a safer and more eco-friendly industrial process.
Objective
SEPARATIVE SAS is an industrial startup located in the heart of the “Chemical Valley” in France, surrounded by major pharmaceutical and chemical companies. We have designed, developed, manufactured a small series, and achieved a breakthrough multicapillary material that solves problems related to purification in the pharmaceutical and chemical industries. From this innovation, we have obtained 5 patents for the material and its manufacturing process. Our chromatography column, SEP43, is the first to meet the industry need to purify molecules to high purity quickly and at low pressure.
Purification is key for all chemical industries. Yet, current techniques are expensive, slow, energy intensive, and create issues for health, safety and the environment. Hence, purification has become a lock in drug discovery. SEP43 would enable faster drug and chemical development, at lower cost, with a safer and more eco-friendly manufacturing process. This is in line with the European Green Deal as the use of our product would save up to 20,000 mt of CO2E from solvent incineration, 8000kw/h electricity consumption and solvent cost of €9.6M/year.
The current pharmaceutical chromatography market is worth over 3B€. Our technology is well-positioned to rapidly become the preferred solution for both R&D and process-scale purification. Our strategy is to enter the market in drug discovery and to follow the molecule life cycle toward the process-scale before branching out to other chemical sectors. This first business case will generate the needed cash flow to invest in further product development and promotion.
Our prototypes have been successfully tested at TRL6 by independent laboratories. But as an equity-intensive and deep-tech project, we have been unable to attract sufficient funding to scale-up and automate our production line. The current project would enable us to deploy this strategy and provide a much-needed breakthrough that can be rapidly adopted by a very large market.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been human-validated.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been human-validated.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.3. - PRIORITY 'Societal challenges
See all projects funded under this programme -
H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-2 - SME instrument phase 2
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
69190 Saint Fons
France
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.