Objective
The proposal concerns the study of interactions between polyoxometalates and biomelecular systems, including proteins and carbohydrates. Polyoxometalates (POMs) are early transition metal-oxygen anionic molecular nanoclusters. In addition of numerous other positive properties, some POMs exhibit anti-bacterial, anti-viral, anti-tumor, anti cancer activities or are observed to reduce the symptoms of diabetis.
However, the detailed mechanisms of these phenomena at the molecular level remain elusive. This project is aimed at shedding some light on the matter, in order to open the way for a rational application of POMs in the medical domain. The proposal is highly multidisciplinary and involves collaboration between a number of research groups.
For example, collaboration with group expert in the synthesis of new POMs will be useful to enlarge the impressive number and variety of nanoclusters already available in the host group. The characterisation of the nanostructures will involve detailed X-ray analysis of the superstructures and various electron microscopic techniques. Selection, purification and/or modification of proteins and the synthesis of rationally designed carbohydrates necessitate work with biochemists and scientists familiar with glycolipids.
The evaluation of the biological activity of POMs will also be studied in collaboration. Nanoscience, in which POMs participate, is believed to be an area of research most likely to produce breakthroughs and European Commission has marked this field as one of its high priority research areas, taking into account the high potential for innovative applications.
Health is another area of constant concern. The results of the present research project are expected to impact positively two issues among currently important topics. For intellectual properties, the guidelines of the European Commission will be strictly adhered to. A detailed indicative work plan is proposed in Europe and back to China.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences biochemistry biomolecules carbohydrates
- medical and health sciences clinical medicine oncology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-7
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
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Coordinator
BEIJING
China
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.