Objective
This project sets out to develop a novel prototype acoustic biosensor for use in the detection of microbial pathogens and spoilage organisms in food.
Research has been carried out in order to exploit the aspect of immunological specificity coupled to acoustic based transducer technology for the detection of spoilage/pathogenic microorganisms in food.
The work has involved:
the nucleotide sequence determination of a ferric siderophore receptor protein from Pseudomonas strain M114 domain analysis of the receptor protein to identify surface exposed regions and to generate antibodies directed agaisnt such regions;
analysis of the adsorption of radiolabelled immunoglobulin G (IgG) to silver and lithium niobate surfaces;
fabrication, electrical characterization and analysis of the performance of surface acoustic wave (SAW) devices in liquid environments;
design and construction of SAW devices;
assessment of the specificity of developed antibodies.
Biotechnology and microelectronics are brought together in this pre-competitive project. The project is concerned with:
1. Identification of novel surface antigens for the detection of particular strains/species of bacteria;
2. Development of poly- and monoclonal antibodies to these surface antigens;
3. Evaluation of these developed antibodies with regard to species/strain specificity;
4. Acoustic wave transducer design for biosensor applications;
5. Modelling of surface acoustic wave (SAW) transducer devices;
6. Definition, development and optimisation of an acoustic transducer fabrication process;
7. Development of interfacial chemistries to covalently attach antibodies to the transducer surface;
8. Comparison of the newly developed prototype acoustic biosensor with the available technologies for the detection of pathogenic and spoilage bacteria in food.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences chemical sciences inorganic chemistry alkali metals
- natural sciences chemical sciences inorganic chemistry transition metals
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences physical sciences electromagnetism and electronics microelectronics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
30 Cork
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.