Objective
OBTAIN COMPLEX ANTIGENS ALLOWING THE DEVELOPMENT OF IMMUNITY AGAINST FOOT AND MOUTH DISEASE VIRUS, AND MAYBE OBTENTION OF A SAFE AND CHEAPER VACCINE AGAINST FOOT AND MOUTH DISEASE.
The project aimed at the synthesis in baker's yeast of a hybrid virus like particle comprising the surface antigen of the virus which caused hepatitis B in man, and part of a surface protein from foot and mouth disease virus (FMDV). Many yeast strains were genetically engineered by recombinant deoxyribonucleic acid (DNA) techniques, producing hybrid virus like particles in which the FMDV portion was present at different sites. It is hoped that these studies will shed light on the question of which parts of the FMDV are essential and how they must be presented to the immune system, in order to protect target animals against the disease.
THE OBJECTIVE OF THE PROGRAMME IS TO DEVELOP A HIGHLY IMMUNOGENIC COMPLEX CONTAINING FMDV ANTIGENIC DETERMINANTS AGAINST DIFFERENT TYPES OF THE VIRUS. THE POLYVALENT SUB-UNIT VACCINE WILL BE PRODUCED BY RECOMBINANT DNA TECHNIQUES, ASSOCIATING FMVD ANTIGENIC DETERMINANTS WITH HEPATITIS B SURFACE ANTIGENS. THESE RECOMBINANT PARTICLES WILL BE EXPRESSED IN YEAST OR ANIMAL CELLS, AND ANALYZED FOR THEIR IMMUNOLOGICAL PROPERTIES.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology virology
- natural sciences biological sciences genetics DNA
- medical and health sciences health sciences infectious diseases
- medical and health sciences basic medicine immunology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Data not available
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
EH9 3JR Edinburgh
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.