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Content archived on 2024-04-15

NEW IN VITRO INTEGRATED APPROACH TO PHARMACO-TOXICOLOGY AND METABOLISM IN CANCER THERAPY. STRUCTURE-ACTIVITY REQUIREMENTS OF ECTONUCLEOTIDASES

Objective


Predictive in vitro models have been developed for assessing the therapeutic efficiency and the toxicity (mainly hepatoxicity), including metabolic profiles of anticancer drugs. These include: improving methods for primary culture of human cancer cells; selecting multidrug resistant human cancer cell lines; isolation, cryopreservation and culture of human hepatocytes; development of an organ slicing technique. The integrated set of in vitro models are routinely used in drug development.

Fields of science (EuroSciVoc)

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

CENTRO DE INVESTIGACION DEL HOSPITAL DE LA FE "SEVASA"
EU contribution
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Address
HOSPITAL DE LA FE "SEVASA" AVDA.DE CAMPANAR 21
46009 VALENCIA
Spain

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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