Objective
PROJECT 1: MECHANISMS GOVERNING PARTICLE TRANSLOCATION AND RELATED ASPECTS OF LUNG FUNCTION.
THE PRIMARY AIM IS TO CLARIFY THOSE CELLULAR AND PHYSIOLOGICAL PROCESSES WHICH DETERMINE THE MOVEMENT OF PARTICLES WITHIN THE RESPIRATORY TRACT, ESPECIALLY TO SITES WHICH ARE IMPORTANT IN LUNG DOSIMETRY.
PROJECT 2: SPATIAL DISTRIBUTION OF PARTICLES IN THE LUNG IN RELATION TO CELLS AT RISK.
THE AIM IS TO MAKE A QUANTITATIVE ASSESSMENT OF THE ACTUAL SPATIAL DISTRIBUTION OF PARTICLES AT LONG TIMES AFTER INHALATION.
Mechanisms governing particle translocation and related aspects of lung function have been studied as has the spatial distribution of particles in the lung in relation to cells at risk. The data from the short term studies confirm that the microinjection technique results in a pattern of deposition where nearly all of the particles are in subpleural alveoli, with a small proportion in alveoli a few hundred micrometres deeper into the lung, but withno deposition on any of the ciliated airways. Hence it is possible by this technique to study clearance specifically from the alveolar region of the lung and to study the movement of particles resolved over quite small distances within the lung.
1. MECHANISMS GOVERNING PARTICLE TRANSLOCATION AND RELATED ASPECTS OF LUNG FUNCTION.
2. SPATIAL DISTRIBUTION OF PARTICLES IN THE LUNG IN RELATION TO CELLS AT RISK.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
W1N 4AL London
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.