Objective
EVALUATION OF RISKS FROM RADIATION-INDUCED CANCER.
MECHANISMS AND RISKS OF BONE CANCER FROM INCORPORATED RADIONUCLIDES.
The activation of proviral genes and their interaction with cellular oncogenes, in radiation carcinogenesis, was studied by 2 approaches.
First, the activation of endogenous retroviruses during the early latent period of radiation induced osteosarcomagenesis, as well as in induced tumours, and the pathogenicity of various virus isolates was studied in different mouse strains. Radiation induced osteosarcomas were investigated for retrovirus and protooncogene rearrangement and amplification.
Second, cell and tissue culture models were applied to establish the molecular and morphological events during normal osteogenic differentiation and to characterise retrovirus and oncogen induced effects on skeletal cells in vitro.
1. RADIATION-INDUCED ONCOGENESIS UNDER DIFFERENT EXPOSURE CONDITIONS.
2. PATHOGENESIS OF RADIATION-INDUCED CANCER.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology virology
- medical and health sciences clinical medicine oncology
- natural sciences chemical sciences nuclear chemistry radiation chemistry
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
85764 NEUHERBERG
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.