Objective
Radiation induced delays in cell cycle progression have been measured for alpha particles and heavy ion beams using asynchronous cell populations. These measurements, using cytofluorometric methods, show partially contradictory results and are difficult to correlate with measurements of cell cycle delay using the mitotic index or PLM methods. An interpretation of these experiments is difficult because they were performed with asynchronous cell populations. In this case, the measured deoxyribonuceic acid (DNA) spectra were only sensitive to relative changes within the population of the cell cycle phases. A simultaneous slowing down of all cells in all phases does not change the relative proportion of cells in different phases and therefore cannot be detected using this method.
1. MEASUREMENT OF CHROMOSOMAL ABERRATIONS IN MAMMALIAN CELLS INDUCED BY A WIDE VARIETY OF DIFFERENT RADIATION QUALITIES INCLUDING ULTRA DENSELY IONIZING HEAVY CHARGED PARTICLES.
EXPECTED BENEFITS
EVALUATION OF GENETIC RISKS FROM IONIZING RADIATION. DETERMINATION OF GENETIC DAMAGE IN MAN ON THE BASIS OF CHROMOSOME ABERRATIONS INDUCED BY HIGH LET RADIATION.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics DNA
- natural sciences physical sciences nuclear physics
- natural sciences biological sciences genetics chromosomes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
DARMSTADT
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.