Objective
The research in the laboratories involved in the programme is focused on various areas related to the secretion of proteins. These include isolation and characterisation of genes which are involved or enhance secretion, the glycosylation of proteins and its significance, the influence of production conditions on protein secretion, strategies for heterologous protein secretion and studies on protein targeting and secretion at the sub-cellular level.
In total 6 meetings have been held in collaboration with the concerted action group co-ordinated by Dr C A M J J van den Hondel during the programme. The first was held in November 1993, in Amsterdam, and provided an opportunity for the partners to become acquainted with the activities in the participating laboratories. The meeting was highly profitable leading to exchanges at several levels eg research ideas, use of different techniques etc. The second meeting held in Lunteren in April 1994 took the form of a general forum dealing with a range of topics relevant to protein secretion in fungi. The third meeting in November 1994 was part of a larger meeting, held in London, which brought together all the groups engaged in fungal biochemistry, genetics and molecular biology under the aegis of the 3rd Framework Biotechnology Programme. This meeting provided the opportunity for the group as a whole to make decisions concerning a major application to the 4th Framework Programme. The groups meet in Helsinki in May 1995, in Vienna in November 1995 and in Toulouse in May 1996. On each occasion presentations of ongoing research were made and wide ranging discussions focussed on further new ideas and technical developments. In the later stages of the programme the meeting of the CAP groups was held simultaneously with the BIOTECH Project Grant group (which developed from the two CAPs) enabling a sharing of the research being carried out on the important research project on protein secretion. During the course of the programme a range of one-to one discussions between the individual partners have also been held.
MAJOR BREAKTHROUGHS:
The successful major grant proposal on Filamentous Fungi: a cell factory for the production of proteins and fungal metabolites arose from meetings of the CAP groups and other fungal researchers held in 1994 and 1995.. This project will bring together more than 30 academic and industrial laboratories with a diversity of experimental and technical expertise that would enable major advances in the exploitation of these important organisms.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences microbiology mycology
- natural sciences biological sciences molecular biology
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NG7 2RD Nottingham
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.