Objective
Invasive aspergillosis (IA), a fungal disease acquired from environment and associated with a high morbidity and mortality rate, is an increasing challenge for management of immunocompromised patients. The research project of "EBGA Network" (European Group for research on Biotypes and Genotypes of Aspergillus) aims at :
- a better understanding of the epidemiology of IA through the biodiversity and the genetic polymorphism of Aspergillus. fumigatus,
- developing an optimal strategy of prevention of this infection and designing prophylaxis recommendations at the European level.
"EBGA Network" regroups seven teams from five European countries taking advantage of the participants' expertise in medical mycology, epidemiology, molecular biology, genetic, antifungals and management of a fungal culture collection. In this field, the task of EBGA Network is : i) to determine if the most discriminating characterization of Aspergillus fumigatus infecting strains can contribute to our understanding of the epidemiology of IA, ii) to define the role of the molecular tools in the epidemiological investigation of nosocomial and non-nosocomial Aspergillus infections and to clarify the optimal conditions to suppress the indoor sources of the fungal spores, ii) to determine if the current susceptibility level of fungal isolates to systemic antifungals (existing and under development) can be used to define chemoprophylaxis rules. Genotypic and phenotypic characteristics of several hundreds of A.fumigatus clinical and environmental stains isolated from 100 to 120 well-documented cases of - IA in different immunosuppression types (haematological malignancies, solid organ transplants, long-term corticosteroid therapy, AIDS) - and of bronchopulmonary colonization (lung recipients) will be investigated using several reliable molecular methods, standardized tests of susceptibility to antifungals and to disinfectants and statistical analysis. Then a comprehensive strategy of prevention of IA will be designed, in collaboration with medical experts, European scientific groups specialized in management of fungal infections and also with patients' associations.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences sociology demography mortality
- medical and health sciences health sciences public health epidemiology
- natural sciences biological sciences microbiology mycology
- medical and health sciences health sciences infectious diseases RNA viruses HIV
- natural sciences biological sciences molecular biology
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
38706 La Tronche
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.