Automatic System for Peptide Synthesis

Project Information

Grant agreement ID: BMH4979078

Project closed

Start date 1 August 1997

End date 8 April 1998

Funded under

• Specific research, technological development and demonstration programme in the field of biomedicine and health, 1994-1998

Total cost No data

EU contribution No data

Coordinated by

Talent Srl
Italy

Objective

The main aim of this project programme is represented by the design, the assembly and the test phases of an original system for the automated solid-phase synthesis of biopolymers, eg. petides and proteins. In line with market demands, the synthesise will be designed in order to carry out optimised chain assembly utilising the most widely used chemical strategies, i.e. both t-Boc and Fmoc chemistry. The synthesiser will be operated under computer control through dedicated software that will permit the operator not only to select a specific procedure from a range of different pre-programmed synthetic routes, but also to assemble personalised new ones: thus, the distinctive feature of the apparatus will be its extreme flexibility that will allow an easy up scaling of the process. A further original feature of the apparatus will be its plumbing scheme, which will be designed to facilitate optimization of the process from an engineering point of view: the presence of two reaction vessels (reactor and activator) set in separate hydraulic loops and served by two different pumps with independent delivery lines, will enable different chemical operations to be carried out at the sale time, thus, the total time required for each synthetic cycle will be dramatically reduced. The final goal of this project will be represented by the assembly of suitable devices to monitor the extent of the key reactions of solid phase synthesis process and the formulation of appropriate algorithms to control the entire synthetic process automatically.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.

• natural sciences › computer and information sciences › software
• natural sciences › biological sciences › biochemistry › biomolecules › proteins

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Programme(s)

• FP4-BIOMED 2 - Specific research, technological development and demonstration programme in the field of biomedicine and health, 1994-1998

Topic(s)

Data not available

Call for proposal

Data not available

Funding Scheme

EAW - Exploratory awards

Coordinator

Talent Srl

• EU contribution: No data
• Address: Via Follatoio 12 ; 34148 Trieste ; Italy
• Total cost: No data

Participants (1)

OMNIFIT limited

United Kingdom

• EU contribution: No data
• Address: 2,Coldhams lane 2 ; CB1 3HD Cambridge
• Total cost: No data