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The prevention of pelvic inflammatory disease with particular respect to screening for Chlamydia Trachomatis

Objective

Objectives:
- To assess effective methods of screening for chlamydia in women
- To study the prevalence of chlamydial infection in Europe
- To assess the costs and benefits of screening for chlamydia in women
- To devise strategies to reduce the prevalence and sequelae of chlamydial infection
- To assess the long term sequelae of PID, particularly ectopic pregnancy and infertility
- To enhance public awareness of chlamydial infection and PID in women

Brief description:
Pelvic inflammatory disease (PID) is the most serious and costly sexually transmitted disease that effects women. Infection is likely to result in chronic ill-health, infertility and ectopic pregnancy. Chlamydia Trachomatis is the major cause of PID and is the most common sexually transmitted bacterium in the developed world. There is evidence that screening programmes for chlamydia can be cost effective and likely to result in a reduction in the incidence of PID. Recent advances in screening technology indicate that widespread screening among men and women may be both feasible and acceptable. However the efficacy and cost effectiveness of such strategies need to be assessed.
It is proposed to develop and assess effective methods of screening for lower tract infection in women, as well as compare prevalence of chlamydial infection in both men and women in different European settings. An important issue will be the critical study of the cost effectiveness of screening for chlamydia. It is intended to devise and test strategies to reduce the prevalence and sequelae of chlamydial infection while developing robust means of measuring the long term sequelae. Thus our studies have the major aim of introducing effective preventive measures for PID, while at the same time raising the level of awareness of this major public health problem.

Keywords:
PID, infertility, ectopic pregnancy, Chlamydia Trachomatis, screening, DNA tests, randomised studies, primary prevention, secondary prevention

Funding Scheme

CON - Coordination of research actions

Coordinator

University of Aberdeen
Address
Cornhill Road
AB9 2ZD Aberdeen
United Kingdom