Objective
Harmony (Harmonisation of Antibiotic Resistance measurement, methods of typing organisms and ways of using these and other tools to increase the effectiveness of Nosocomial Infection control) will comprise a resource, facilitating centers, an international network of opinion leaders and centers of excellence, interact with the various networks of hospitals and target four areas as follows: &L- Antibiotic susceptibility testing To introduce or augment existing continuous quality improvement systems of antibiotic susceptibility testing and thus provide a credible basis for describing and monitoring the extent of the problem of antibiotic resistance in participating countries. &L- Microbial Typing <o establish strains and other mechanisms to harmonise and standardise "DNA fingerprinting" to become genuine typing systems, disseminate the improved methodology to all participating countries and design joint experiments to explore the applicability, variability and other matters raised by the group. To assess what new and old antibiotics Infection control teams (ICTs) should test as an extended antibiotic resistotyping tool for the targeted antibiotic resistant organisms (AROs). These will be reported to the center and inform the database (see IV) as well as provide data on the available therapeutic options against important bacterial strains causing hospital infection. We will also examine the cost, effectiveness and feasibility of also using chemical resistotyping as an initial ICT typing system for methicillin-resistant Staphylococcus aureus (MRSA). &L- Infection control, antibiotic therapy policy and audit Facilitate the production of "bottom-up" policies and audit tools: &Li) to increase the power and focus of typing data by agreeing the criteria for submission of isolates for typing, the demographic and epidemiological information accompanying them and audit compliance with these standards and assess how the typing data meets the aims of the ICTs in device related infection and outbreak investigations. &Lii) for device usage, insertion and maintenance &Liii) for methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), antibiotic resistant gram negative rod and Clostridium difficile outbreaks &Liv) of antibiotic therapy and explore the feasibility of using a resistance/use index to examine the effects of antibiotic use and ARO occurrence. &L- Establish a "State of the Art" European interactive database on thc INTERNET of existing and prospectively collected validated antibiotic resistant strains causing HAI together with antibiotic susceptibilities, conventional and computerised DNA typing parameters, agreed parameters of virulence e.g. toxins, lectin spectra, epidemicity, "infection control pedigree" e.g. influence of staff/patient ratios, intensivity of care, case mix so that ICTs can compare their own organisms with these data and prioritise or optimise their infection control strategies. Templates for policies, guidelines and audit tools will also be accessible in this way.&L &L Keywords:&L Typing, Antibiotics, Hospital Infection, Policies, Audit, Quality Assurance, MRSA, VRE, C. difficile
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences internet
- natural sciences computer and information sciences databases
- natural sciences biological sciences genetics DNA
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antibiotics
- medical and health sciences basic medicine pharmacology and pharmacy drug resistance antibiotic resistance
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NW9 5HT LONDON
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.