Objective
The scientific and technical objectives of this research proposal concern pharmaceutical registration of chiral drugs: (+)-zopiclone and 1,4-dihydropyridines. Although it's very well-known the influence of the drug stereochemistry in their activity, up to 1994 most of the chiral drugs are marketed as a racemic mixtures. The biological activity, bioavailability and metabolism of a drug can be very different for each one of the enantiomers of a chiral drug. The growth of the demand of chiral drugs has stimulated the research of new roads for the synthesis of pure enantiomers with therapeutical activity. We are still at the begining of a long way that may lead to the replacement of racemic drugs by the more selective and/or potent and/or safe single enantiomer. Research is required to synthetise the chiral drugs, studie the activity, bioavailability and selectivity of optically pure enantiomers . Also required the optimisation of experimental conditions of scaie-up process.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
33192 Llanera
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.