Objective
A NEW THERMOPHILIC FUNGUS, CL240, WAS SELECTED IN A SCREENING PROGRAM FOR ITS ABILITY TO PRODUCE A VERY BROAD SPECTRUM OF POLYSACCHAROLYTIC ACTIVITIES: CELLULASES, VARIOUS HEMICELLULASES, BETA GLUCANASES, AMYLOGLUCOSIDASE... ALL THESE ENZYMES ARE STABLE AT 70 CELSIUS DEGREES OR MORE. THE SPECIFIC ACTIVITY OF THE CELLULOLYTIC COMPLEX ON CRISTALLINE CELLULOSE, AND THE PRODUCTIVITY OF WILD TYPE STRAINS COMPARE FAVOURABLY WITH THOSE OF TRICHODERMA REESEI.
THE AIM OF THIS RESEARCH PROPOSAL IS THE SCREENING OF MUTANTS OF THIS STRAIN WHOSE SPECIFIC ACTIVITY OF EXTRACELLULAR PROTEINS TOWARDS CRISTALLINE CELLULOSE WILL BE HIGHER THAN THAT OF CELLULASE FROM TRICHODERMA REESEI. CELLULOLYTIC ENZYMES WILL BE PURIFIED BY PREPARATIVE CHROMATOGRAPHY AND THE BEST COMBINATION OF EACH COMPONENT TO GIVE AN INCREASE OF THE SPECIFIC ACTIVITY WILL BE DETERMINED. THE SEARCH OF MUTANTS WILL THEN BE ORIENTED TOWARDS A SPECIFIC INCREASE OF COMPONENTS SUCH AS EXOGLUCANASES WHOSE CONCENTRATION IS LIMITING IN THE CELLULOLYTIC COMPLEX. SELECTION OF MUTANTS WILL BE CARRIED OUT BY CONVENTIONNAL GENETIC PROCEDURE USING ADAPTED SCREENS.
THE EFFICIENCY OF ENZYME PREPARATIONS FROM DIFFERENT MUTANTS IN CONVERTING STEAM EXPLODED CORN STOVERS TO ALCOHOLS FERMENTABLE SUGARS WILL BE ASSESSED.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology mycology
- social sciences economics and business economics production economics productivity
- natural sciences chemical sciences organic chemistry alcohols
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Data not available
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
31062 Toulouse
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.