Objective
Industrial plants, transport systems, etc., are regularly assessed with respect to the risk posed to nearby inhabitants due to accidents which involve the release of toxic chemicals.
The objective of this proposal is to develop and assess methodologies to determine the acute toxicity through inhalation of a number of hazardous substances for fluctuating concentration exposure and lethal and non-lethal damage.
This is relevant because of the concentration fluctuations in any cloud in the atmosphere. This means that in real life during accidental releases exposure may occur during short to very short time periods, separated by periods of zero concentration.
With respect to the toxic impact there is little knowledge about effects of exposure during extreme short periods.
Toxicity data, e.g. as used in the Probit-functions, is generally based on exposure averaged over at least 10 minutes, whereas the relevant timescales of concentration fluctuations can be of the order of a minute or less.
This proposal wants to address this problem by analysing working mechanisms of very acute acting toxic substances, by analysis of some experimental data and by attempting to provide model descriptions of the physical and chemical processes involved in the toxic impact through inhalation. The result will be concentration-time-effect relationships for a number of toxic substances and guidelines on the relevant timescales to be considered in quantitative risk assessment
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
7300 AH Apeldoorn
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.