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Content archived on 2024-04-19

Interlaboratory standardisation and validation of DNA adducts postlabelling methods for human biomarker studies

Objective

The main objective of this project is to standardise the available assay protocols, and to identify the various methodological problems, thus providing guidelines for the use of 32P-postlabelling in detecting carcinogen-DNA adducts so that this procedure can be rationally applied for monitoring human exposure to environmental carcinogens.


Through a series of collaborative studies and brain-storming sessions the project will enable :

1) to provide users of postlabelling methods in various fields with standardized protocols;

2) to improve the methods of identification of individuals in cancer epidemiology who, due to their increased exposure to carcinogens or due to their inherited susceptibility, are at increased risk of developing cancer;

3) to assess the effectiveness of measures to reduce exposure to carcinogens in the work place and

4) to determine the extent to which the use of biomarkers such as DNA adducts are quantitative indicators of cancer risk in humans.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

Centre International de Recherche sur le Cancer
EU contribution
No data
Address
150 cours Albert Thomas
69372 Lyon
France

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (1)

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