Objective
The project integrates in the study of transport pathway and impact of pollutants in the marine ecosystem and aims to understand the effects of trace metals (Hg, Cd, Zn, Cu, Ni, Cr, Pb, Fe) and organochlorines (PCBs, DDT I and dioxin like compounds) on some endocrine and immune functions of one highly treated marine mammal species of the North Sea : the harbour porpoise, Phocoenaphocoena. Immunohistological investigations on thyroid glands will provide information on the potential lesions, as thyroid is one of the major target organs for endocrine disruptors. Detection of cytokines in the blood will be realised using reverse transcription polymerase-chain reaction (RT-PCR). Cytokines are glycoproteinssecreted by immune cells and their gene expression can be strongly modulated by pollutants. Immune and endocrine data will be compared with previously acquired data about heavy metal and organochlorine burden in order to get a better understanding of the mechanism of these pollutant impact.
The multidisciplinary dimension of the project requires the contribution of scientific leaderships in various disciplines(pathology, ecology, immunology, endocrinology and ecotoxicology).specialised in feeding ecology through stable isotope analysis and ecotoxicology and therefore, the realisation of this project needs absolutely the permanent participation of specialists in pathology, endocrinology and immunology of marine mammals. This specialisation can not be found in the Liege University and, thus a long stay of the applicant in the FTZ group will be of the most importance to improve her knowledge in marine mammals immune and endocrine impairments and to help her to get a better understanding on the potential effects of pollutants on marine mammals health status.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences public health
- natural sciences biological sciences zoology mammalogy cetology
- natural sciences biological sciences ecology
- medical and health sciences basic medicine immunology
- medical and health sciences clinical medicine endocrinology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
25761 BUESUM
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.