Objective
Cyclodextrins are a unique group of cyclic glucose oligomers. They are
biotechnologically produced from potato or maize starch to a reasonable price of 6-20 ECU/kg at present.
The main objective of this proposal is to initiate a breakthrough for industrial
applications of cyclodextrins. Therefore the interesting inclusive properties of
cyclodextrins are to be used to retard, transport, separate and detect active substances. These functions will lead to a great variety of applications : improved drug delivery and slow release of active substances, refined pharmaceuticals, decontamination of waste waters and detection of poisons in the environment.
The main objective is going to be reached within the following subprojects :
- development of highly active cyclodextrin based resins for the decontamination
of waste waters. Pollutants like chlorinated biphenyls are going to be removed
by filtration techniques;
- search for new large scale separation processes for stereoisomers by two phase
separation systems, e.g. liquid/liquid or crystalline/liquid. These processes are
of special interest as they can be carried out in high quantities (tons) and both
batch and continuously;
- development of specific chromatographic systems for the analytical and
semipreparative separation of enantiomers. Special emphasis will be on
advanced chromatographic techniques like supercritical fluid chromatography
and capillary electrophoresis;
- development of highly specific sensor devices from cyclodextrins. State of art
waveguide technology will be used to construct devices for the fast and
continuous detection of small amounts of dangerous pollutants in the
environment;
- design of cyclodextrin derivatives for the programmed targeting of drugs in the
human body. Cyclodextrins have to be labelled with recognition sites for the
desired destination in the body. Targeting of drugs has raised great attention in
medicine as it minimizes undesirable side effects of drugs;
- development of procedures for well defined and stable coatings of surfaces with
cyclodextrin derivatives, especially cyclodextrin polymers. Surfaces of metals,
textiles, paper and polymers have to be considered. This surface modification
can be applied for thermotransfer printing, to improve dye adhesion, for
antistatics or for anti-bacterial protection.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology environmental engineering water treatment processes wastewater treatment processes
- agricultural sciences agricultural biotechnology
- engineering and technology materials engineering textiles
- engineering and technology materials engineering coating and films
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
76187 KARLSRUHE
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.